Human Gene CLTRN (ENST00000650271.1) from GENCODE V41
Description: collectrin, amino acid transport regulator (from HGNC CLTRN) RefSeq Summary (NM_020665): This gene encodes a type 1 transmembrane protein that is important for trafficking amino acid transporters to the apical brush border of proximal tubules. The encoded protein binds to amino acid transporters and regulates their expression on the plasma membrane. It also plays a role in controlling insulin exocytosis by regulating formation of the SNARE (soluble N-ethylmaleimide-sensitive-factor attachment protein receptor) complex in pancreatic beta cells. The extracellular domain of the encoded protein may be cleaved and shed from the plasma membrane specifically in pancreatic beta cells. [provided by RefSeq, Jun 2013]. Gencode Transcript: ENST00000650271.1 Gencode Gene: ENSG00000147003.7 Transcript (Including UTRs) Position: hg38 chrX:15,627,439-15,675,012 Size: 47,574 Total Exon Count: 7 Strand: - Coding Region Position: hg38 chrX:15,627,971-15,659,062 Size: 31,092 Coding Exon Count: 4
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.