Mouse Gene Slc25a15 (ENSMUST00000033871.8) from GENCODE VM33
  Description: Mus musculus solute carrier family 25 (mitochondrial carrier ornithine transporter), member 15 (Slc25a15), transcript variant 1, mRNA; nuclear gene for mitochondrial product. (from RefSeq NM_181325)
Gencode Transcript: ENSMUST00000033871.8
Gencode Gene: ENSMUSG00000031482.10
Transcript (Including UTRs)
   Position: mm39 chr8:22,865,567-22,888,613 Size: 23,047 Total Exon Count: 7 Strand: -
Coding Region
   Position: mm39 chr8:22,867,873-22,885,783 Size: 17,911 Coding Exon Count: 6 

Page IndexSequence and LinksUniProtKB CommentsPrimersCTDRNA Structure
Protein StructureOther SpeciesGO AnnotationsmRNA DescriptionsOther NamesMethods
Data last updated at UCSC: 2023-08-15 19:06:27

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr8:22,865,567-22,888,613)mRNA (may differ from genome)Protein (301 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneTable SchemaAlphaFold
BioGPSEnsemblEntrez GeneExonPrimerGeneCardsMGI
PubMedSOURCEUniProtKB

-  Comments and Description Text from UniProtKB
  ID: ORNT1_MOUSE
DESCRIPTION: RecName: Full=Mitochondrial ornithine transporter 1; AltName: Full=Solute carrier family 25 member 15;
FUNCTION: Ornithine transport across inner mitochondrial membrane, from the cytoplasm to the matrix.
SUBCELLULAR LOCATION: Mitochondrion inner membrane; Multi-pass membrane protein.
SIMILARITY: Belongs to the mitochondrial carrier family.
SIMILARITY: Contains 3 Solcar repeats.

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -116.70218-0.535 Picture PostScript Text
3' UTR -715.502306-0.310 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR018108 - Mitochondrial_sb/sol_carrier
IPR023395 - Mt_carrier_dom

Pfam Domains:
PF00153 - Mitochondrial carrier protein

ModBase Predicted Comparative 3D Structure on Q9WVD5
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The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
HumanRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserGenome BrowserGenome BrowserGenome BrowserNo ortholog
Gene Details     
Gene Sorter     
GenBankRGDEnsemblEnsemblWormBase 
Protein SequenceProtein SequenceProtein SequenceProtein SequenceProtein Sequence 
AlignmentAlignmentAlignmentAlignmentAlignment 

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0000064 L-ornithine transmembrane transporter activity

Biological Process:
GO:0006839 mitochondrial transport
GO:1903352 L-ornithine transmembrane transport

Cellular Component:
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0016020 membrane
GO:0016021 integral component of membrane


-  Descriptions from all associated GenBank mRNAs
  AK142223 - Mus musculus 13 days embryo heart cDNA, RIKEN full-length enriched library, clone:D330014F10 product:solute carrier family 25 (mitochondrial carrier; ornithine transporter), member 15, full insert sequence.
AK154988 - Mus musculus NOD-derived CD11c +ve dendritic cells cDNA, RIKEN full-length enriched library, clone:F630113O08 product:solute carrier family 25 (mitochondrial carrier; ornithine transporter), member 15, full insert sequence.
AK145966 - Mus musculus 14 days pregnant adult female amnion cDNA, RIKEN full-length enriched library, clone:I530018K18 product:solute carrier family 25 (mitochondrial carrier; ornithine transporter), member 15, full insert sequence.
AK052758 - Mus musculus 0 day neonate kidney cDNA, RIKEN full-length enriched library, clone:D630044L02 product:solute carrier family 25 (mitochondrial carrier; ornithine transporter), member 15, full insert sequence.
AK081243 - Mus musculus adult male corpus striatum cDNA, RIKEN full-length enriched library, clone:C030019P07 product:similar to ORNITHINE TRANSPORTER 2 [Homo sapiens], full insert sequence.
AF133914 - Mus musculus ornithine transporter mRNA, complete cds; nuclear gene for mitochondrial product.
BC061143 - Mus musculus solute carrier family 25 (mitochondrial carrier ornithine transporter), member 15, mRNA (cDNA clone MGC:74275 IMAGE:30276598), complete cds.
AK190978 - Mus musculus cDNA, clone:Y1G0104G19, strand:minus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000070698, based on BLAT search.

-  Other Names for This Gene
  Alternate Gene Symbols: ENSMUST00000033871.1, ENSMUST00000033871.2, ENSMUST00000033871.3, ENSMUST00000033871.4, ENSMUST00000033871.5, ENSMUST00000033871.6, ENSMUST00000033871.7, NM_181325, Ornt1, ORNT1_MOUSE, Q9WVD5, uc009lcz.1, uc009lcz.2, uc009lcz.3, uc009lcz.4
UCSC ID: ENSMUST00000033871.8
RefSeq Accession: NM_181325
Protein: Q9WVD5 (aka ORNT1_MOUSE or ORT1_MOUSE)

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.