Mouse Gene Slc25a53 (ENSMUST00000113069.9) from GENCODE VM33
  Description: Mus musculus solute carrier family 25, member 53 (Slc25a53), transcript variant 1, mRNA. (from RefSeq NM_001082412)
Gencode Transcript: ENSMUST00000113069.9
Gencode Gene: ENSMUSG00000044348.15
Transcript (Including UTRs)
   Position: mm39 chrX:135,881,865-135,939,049 Size: 57,185 Total Exon Count: 7 Strand: -
Coding Region
   Position: mm39 chrX:135,883,419-135,916,094 Size: 32,676 Coding Exon Count: 2 

Page IndexSequence and LinksUniProtKB CommentsPrimersCTDRNA Structure
Protein StructureOther SpeciesGO AnnotationsmRNA DescriptionsOther NamesMethods
Data last updated at UCSC: 2023-08-15 19:06:27

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chrX:135,881,865-135,939,049)mRNA (may differ from genome)Protein (346 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneTable SchemaAlphaFold
BioGPSEnsemblEntrez GeneExonPrimerGeneCardsMGI
PubMedSOURCEUniProtKB

-  Comments and Description Text from UniProtKB
  ID: A2AF28_MOUSE
DESCRIPTION: SubName: Full=MCG115034, isoform CRA_c; SubName: Full=Mitochondrial carrier triple repeat 6; SubName: Full=Protein Mcart6;
SIMILARITY: Belongs to the mitochondrial carrier family.

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -205.70594-0.346 Picture PostScript Text
3' UTR -363.801554-0.234 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR018108 - Mitochondrial_sb/sol_carrier
IPR023395 - Mt_carrier_dom

Pfam Domains:
PF00153 - Mitochondrial carrier protein

ModBase Predicted Comparative 3D Structure on A2AF28
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The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
HumanRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
GenBank     
Protein Sequence     
Alignment     

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0022857 transmembrane transporter activity

Biological Process:
GO:0006839 mitochondrial transport
GO:0055085 transmembrane transport

Cellular Component:
GO:0005743 mitochondrial inner membrane
GO:0016020 membrane
GO:0016021 integral component of membrane


-  Descriptions from all associated GenBank mRNAs
  LF202251 - JP 2014500723-A/9754: Polycomb-Associated Non-Coding RNAs.
MA437828 - JP 2018138019-A/9754: Polycomb-Associated Non-Coding RNAs.
AK076279 - Mus musculus 0 day neonate skin cDNA, RIKEN full-length enriched library, clone:4632409G01 product:unclassifiable, full insert sequence.
AK028496 - Mus musculus 0 day neonate skin cDNA, RIKEN full-length enriched library, clone:4632404B18 product:unclassifiable, full insert sequence.
AK012963 - Mus musculus 10, 11 days embryo whole body cDNA, RIKEN full-length enriched library, clone:2810402A17 product:unclassifiable, full insert sequence.
BC024604 - Mus musculus mitochondrial carrier triple repeat 6, mRNA (cDNA clone IMAGE:4458232), with apparent retained intron.
AK013345 - Mus musculus 10, 11 days embryo whole body cDNA, RIKEN full-length enriched library, clone:2810454J05 product:unclassifiable, full insert sequence.
BC152775 - Synthetic construct Mus musculus clone IMAGE:100016016, MGC:184390 mitochondrial carrier triple repeat 6 (Mcart6) mRNA, encodes complete protein.
AK049939 - Mus musculus adult male hippocampus cDNA, RIKEN full-length enriched library, clone:C630013E09 product:RIKEN cDNA 2810402A17 gene, full insert sequence.
AK009846 - Mus musculus adult male tongue cDNA, RIKEN full-length enriched library, clone:2310046F18 product:unclassifiable, full insert sequence.
LF315628 - JP 2014500723-A/123131: Polycomb-Associated Non-Coding RNAs.
MA551205 - JP 2018138019-A/123131: Polycomb-Associated Non-Coding RNAs.

-  Other Names for This Gene
  Alternate Gene Symbols: A2AF28, A2AF28_MOUSE, ENSMUST00000113069.1, ENSMUST00000113069.2, ENSMUST00000113069.3, ENSMUST00000113069.4, ENSMUST00000113069.5, ENSMUST00000113069.6, ENSMUST00000113069.7, ENSMUST00000113069.8, Mcart6, mCG_115034, NM_001082412, RP23-389M3.8-001, uc009ujj.1, uc009ujj.2, uc009ujj.3, uc009ujj.4
UCSC ID: ENSMUST00000113069.9
RefSeq Accession: NM_001082412
Protein: A2AF28

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.