ID:SCMC2_MOUSE DESCRIPTION: RecName: Full=Calcium-binding mitochondrial carrier protein SCaMC-2; AltName: Full=Small calcium-binding mitochondrial carrier protein 2; AltName: Full=Solute carrier family 25 member 25; FUNCTION: Calcium-dependent mitochondrial solute carrier. Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. May act as a ATP-Mg/Pi exchanger that mediates the transport of Mg-ATP in exchange for phosphate, catalyzing the net uptake or efflux of adenine nucleotides into or from the mitochondria (By similarity). SUBCELLULAR LOCATION: Mitochondrion inner membrane; Multi-pass membrane protein (By similarity). SIMILARITY: Belongs to the mitochondrial carrier family. SIMILARITY: Contains 3 EF-hand domains. SIMILARITY: Contains 3 Solcar repeats. SEQUENCE CAUTION: Sequence=AAH19978.1; Type=Erroneous initiation; Sequence=AAH22114.1; Type=Erroneous initiation; Sequence=BAC65850.1; Type=Erroneous initiation; Sequence=CAM18798.1; Type=Erroneous gene model prediction; Sequence=CAM18799.1; Type=Erroneous gene model prediction;
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Pfam Domains: PF00153 - Mitochondrial carrier protein PF13202 - EF hand PF13499 - EF-hand domain pair PF13833 - EF-hand domain pair
SCOP Domains: 63446 - Type I dockerin domain 47473 - EF-hand 103506 - Mitochondrial carrier
ModBase Predicted Comparative 3D Structure on A2ASZ8
Front
Top
Side
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Molecular Function: GO:0005347 ATP transmembrane transporter activity GO:0005509 calcium ion binding GO:0015217 ADP transmembrane transporter activity GO:0046872 metal ion binding
US Server
