- Home
- Genomes
- Genome Browser
- Tools
- Mirrors
- Downloads
- My Data
- Projects
- Help
- About Us
p21 → Rho: " Rho regulates p21 ( CIP1 ), cyclin D1, and checkpoint control in mammary epithelial cells "
cyclin → Rho: " Rho regulates p21 ( CIP1 ), cyclin D1, and checkpoint control in mammary epithelial cells "
Rho → EGF: " Here, we demonstrate that Rho is required for G1 to S progression in MCF10A mammary epithelial cells, both in response to EGF and in response to oncogenic Ras "
Rho ⊣ p21: " The Rho inhibitor, C3 exotransferase, induced p21 ( CIP1 ) both in EGF stimulated and V12Ras expressing cells "
cyclin D1 → EGF: " In addition, C3 blocked EGF stimulated cyclin D1 promoter activity whereas V14RhoA induced the cyclin D1 promoter and cooperated with V12Ras in cyclin D1 induction "
cyclin D1 → V14RhoA: " In addition, C3 blocked EGF stimulated cyclin D1 promoter activity whereas V14RhoA induced the cyclin D1 promoter and cooperated with V12Ras in cyclin D1 induction "
p21 ⊣ Rho: " Our results demonstrate that Rho plays a fundamental role in promoting Ras dependent S phase entry in mammary epithelial cells, whether in response to normal or oncogenic signaling, and indicate that in cells expressing oncogenic Ras, the activation of Rho diminishes p21 ( CIP1 ) expression, increases cyclin D1 promoter activity, and uncouples DNA synthesis from mitosis "
cyclin D1 → Rho: " Our results demonstrate that Rho plays a fundamental role in promoting Ras dependent S phase entry in mammary epithelial cells, whether in response to normal or oncogenic signaling, and indicate that in cells expressing oncogenic Ras, the activation of Rho diminishes p21 ( CIP1 ) expression, increases cyclin D1 promoter activity, and uncouples DNA synthesis from mitosis "