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BRCA1 → IFN-gamma: " Using an Affymetrix U95A microarray, IRF-7 was identified as a BRCA1 transcriptional target and was also shown to be synergistically up-regulated by BRCA1 specifically in the presence of IFN-gamma , coincident with the synergistic induction of apoptosis "
IRF-7 → BRCA1: " Using an Affymetrix U95A microarray, IRF-7 was identified as a BRCA1 transcriptional target and was also shown to be synergistically up-regulated by BRCA1 specifically in the presence of IFN-gamma, coincident with the synergistic induction of apoptosis "
IRF-7 → IFN-gamma: " Using an Affymetrix U95A microarray, IRF-7 was identified as a BRCA1 transcriptional target and was also shown to be synergistically up-regulated by BRCA1 specifically in the presence of IFN-gamma , coincident with the synergistic induction of apoptosis "
IRF-7 → BRCA1: " We show that BRCA1 , signal transducer and activator of transcription ( STAT ) -1, and STAT2 are all required for the induction of IRF-7 following stimulation with IFN-gamma "
IRF-7 → STAT2: " We show that BRCA1, signal transducer and activator of transcription ( STAT ) -1, and STAT2 are all required for the induction of IRF-7 following stimulation with IFN-gamma "
IRF-7 → BRCA1: " We also show that the induction of IRF-7 by BRCA1 and IFN-gamma is dependent on the type I IFNs, IFN-alpha and IFN-beta "
IRF-7 → IFN-gamma: " We also show that the induction of IRF-7 by BRCA1 and IFN-gamma is dependent on the type I IFNs, IFN-alpha and IFN-beta "
STAT1 → BRCA1: " We show that BRCA1 is required for the up-regulation of STAT1 , STAT2, and the type I IFNs in response to IFN-gamma "
STAT1 → IFN-gamma: " We show that BRCA1 is required for the up-regulation of STAT1 , STAT2, and the type I IFNs in response to IFN-gamma "
STAT2 → BRCA1: " We show that BRCA1 is required for the up-regulation of STAT1, STAT2 , and the type I IFNs in response to IFN-gamma "
STAT2 → IFN-gamma: " We show that BRCA1 is required for the up-regulation of STAT1, STAT2 , and the type I IFNs in response to IFN-gamma "
IRF-7 → IFN-beta: " Blocking this intermediary type I IFN step using specific antisera shows the requirement for IFN-alpha and IFN-beta in the induction of IRF-7 and apoptosis "