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MAPK ⊣ IL-1 receptor antagonist (IL-1ra): " I.t. pretreatment of IL-1 receptor antagonist (IL-1ra) , p38 MAPK inhibitor or iNOS inhibitor, inhibits the i.t. IL-1beta induced NO levels and thermal hyperalgesia in rats, likely via either inhibiting the IL-1beta mediated p38 MAPK activation and subsequent iNOS induction, or direct attenuation of the central iNOS activity, which therefore reduces the central sensitization of inflammatory pain "
iNOS ⊣ IL-1 receptor antagonist (IL-1ra): " I.t. pretreatment of IL-1 receptor antagonist (IL-1ra) , p38 MAPK inhibitor or iNOS inhibitor , inhibits the i.t. IL-1beta induced NO levels and thermal hyperalgesia in rats, likely via either inhibiting the IL-1beta mediated p38 MAPK activation and subsequent iNOS induction, or direct attenuation of the central iNOS activity, which therefore reduces the central sensitization of inflammatory pain "
p38 → IL-1beta: " I.t. pretreatment of IL-1 receptor antagonist (IL-1ra), p38 MAPK inhibitor or iNOS inhibitor, inhibits the i.t. IL-1beta induced NO levels and thermal hyperalgesia in rats, likely via either inhibiting the IL-1beta mediated p38 MAPK activation and subsequent iNOS induction, or direct attenuation of the central iNOS activity, which therefore reduces the central sensitization of inflammatory pain "
p38 → iNOS: " I.t. pretreatment of IL-1 receptor antagonist (IL-1ra), p38 MAPK inhibitor or iNOS inhibitor, inhibits the i.t. IL-1beta induced NO levels and thermal hyperalgesia in rats, likely via either inhibiting the IL-1beta mediated p38 MAPK activation and subsequent iNOS induction , or direct attenuation of the central iNOS activity, which therefore reduces the central sensitization of inflammatory pain "
MAPK → IL-1beta: " I.t. pretreatment of IL-1 receptor antagonist (IL-1ra), p38 MAPK inhibitor or iNOS inhibitor, inhibits the i.t. IL-1beta induced NO levels and thermal hyperalgesia in rats, likely via either inhibiting the IL-1beta mediated p38 MAPK activation and subsequent iNOS induction, or direct attenuation of the central iNOS activity, which therefore reduces the central sensitization of inflammatory pain "
MAPK → iNOS: " I.t. pretreatment of IL-1 receptor antagonist (IL-1ra), p38 MAPK inhibitor or iNOS inhibitor, inhibits the i.t. IL-1beta induced NO levels and thermal hyperalgesia in rats, likely via either inhibiting the IL-1beta mediated p38 MAPK activation and subsequent iNOS induction , or direct attenuation of the central iNOS activity, which therefore reduces the central sensitization of inflammatory pain "
iNOS → IL-1beta: " I.t. pretreatment of IL-1 receptor antagonist (IL-1ra), p38 MAPK inhibitor or iNOS inhibitor, inhibits the i.t. IL-1beta induced NO levels and thermal hyperalgesia in rats, likely via either inhibiting the IL-1beta mediated p38 MAPK activation and subsequent iNOS induction , or direct attenuation of the central iNOS activity, which therefore reduces the central sensitization of inflammatory pain "