Gene interactions and pathways from curated databases and text-mining
CASP3: top 25 interacting genes (chr4:185548849-185570629)
Mouse over or click genes or lines for details. Dashed lines indicate interactions without text mining support. Click any gene to make it the new center. Click any line to show details about the interaction. Only CASP3-interacting genes and only the most-mentioned/most-curated interactions are shown in the graph. See the Help Page for details.
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Less-frequently mentioned interactions with CASP3, not among the Top 25
Other genes interacting with CASP3. Mouse-over to show number of abstracts or databases. Sorted by article count (sort alphabetically).
Like above, interactions are colored by support. Grey:only text mining, light-blue:interaction database, blue:pathway database

AKT3 ▸ XIAP ▸ IL1B ▸ FASLG ▸ MAPK3 ▸ BCL3 ▸ DIABLO ▸
BCL6 ▸ BCL5 ▸ IL1A ▸ BCL9 ▸ IRF6 ▸ EPHB2 ▸ MAPK1 ▸
MAPK12 ▸ MAPK6 ▸ MAPK10 ▸ MAPK8 ▸ MAPK13 ▸ MAPK14 ▸ MAPK15 ▸
MAPK11 ▸ MAPK9 ▸ MAPK7 ▸ MAPK4 ▸ IFNG ▸ CASP9 ▸ CASP8 ▸
APAF1 ▸ CASP12 ▸ CASP1 ▸ CASP2 ▸ CAPN1 ▸ DNTT ▸ CAPN10 ▸
IL18 ▸ CAPN3 ▸ CAPN2 ▸ CAPN11 ▸ CAPN15 ▸ CAPN14 ▸ CAPN8 ▸
CASP6 ▸ CAPN9 ▸ CAPN12 ▸ CAPN6 ▸ CAPN13 ▸ CAPN5 ▸ CAPN7 ▸
FADD ▸ CASP7 ▸ CASP5 ▸ CASP16 ▸ CASP10 ▸ CASP14 ▸ CASP4 ▸
STS ▸ ASIP ▸ MCL1 ▸ MMP9 ▸ MMP2 ▸ MMP3 ▸ JUN ▸
MMP14 ▸ MMP12 ▸ MMP11 ▸ MMP28 ▸ CDKN1A ▸ MMP16 ▸ MMP24 ▸
MMP8 ▸ MMP13 ▸ MMP21 ▸ MMP20 ▸ NLRP3 ▸ MMP10 ▸ MMP26 ▸
MMP27 ▸ MMP7 ▸ MMP25 ▸ MMP17 ▸ MMP15 ▸ MMP1 ▸ MMP19 ▸
PDCD5 ▸ PDCD11 ▸ PDCD6 ▸ RNF19A ▸ PDCD4 ▸ PDCD2 ▸ PDCD7 ▸
PDCD1 ▸ PDCD10 ▸ CYCS ▸ CFLAR ▸ NA ▸ IGF1 ▸ ANXA5 ▸
PCBD1 ▸ TGFB1 ▸ AHSA1 ▸ INS ▸ HLA-DRB1 ▸ PIK3R1 ▸ PIK3CA ▸
MPZ ▸ EPO ▸ PRKCD ▸ NLRC4 ▸ PI3 ▸ VEGFA ▸ MYLIP ▸
PCNA ▸ TAT ▸ IL6 ▸ DDIT3 ▸ DFFA ▸ GRAP2 ▸ NOS2 ▸
PRDX2 ▸ GSK3B ▸ TNFRSF1A ▸ CRK ▸ NGF ▸ PAK2 ▸ DISC1 ▸
IL8 ▸ BIRC2 ▸ CTSB ▸ SOD1 ▸ EGF ▸ DISC2 ▸ CTNNB1 ▸
IL4 ▸ PTGS2 ▸ EIF2AK2 ▸ CAST ▸ BID ▸ NOS1 ▸ DFFB ▸
LEP ▸ HGF ▸ ABL1 ▸ DNASE2 ▸ ROCK1 ▸ DNASE1 ▸ P2RX7 ▸
ALPI ▸ FOS ▸ SOD2 ▸ IRF1 ▸ APP ▸ MYC ▸ APEH ▸
CDK2 ▸ CAT ▸ BCR ▸ TCF4 ▸ HTRA2 ▸ IFNB1 ▸ CTSD ▸
MAP3K1 ▸ IL16 ▸ IFI27 ▸ BDNF ▸ IL10 ▸ CSF2 ▸ FGF2 ▸
GZMB ▸ TCF21 ▸ TCF7 ▸ GAL ▸ PRKDC ▸ HDAC2 ▸ APOB ▸
NOD2 ▸ TCF24 ▸ TCF25 ▸ TLR2 ▸ TCF3 ▸ UPK3B ▸ HSPA5 ▸
BIRC7 ▸ TCF23 ▸ RAC1 ▸ TCF19 ▸ BMP4 ▸ NOS3 ▸ RIPK1 ▸
SOD3 ▸ NFKBIA ▸ NOX1 ▸ TCF12 ▸ BMP1 ▸ BIRC3 ▸ TCF20 ▸
TCF15 ▸ CD8A ▸ ITIH4 ▸ POLDIP2 ▸ NOX4 ▸ MAGT1 ▸ HDAC1 ▸
AIM2 ▸ CSF3 ▸ CDC73 ▸ TLR4 ▸ MAP2K1 ▸ LMNB1 ▸ BAD ▸
NLRP1 ▸ CA2 ▸ STAT1 ▸ ARSK ▸ ATP5O ▸ IL2 ▸ PML ▸
HMGB1 ▸ ADCYAP1 ▸ TLR3 ▸ PPARA ▸ PPP2R2B ▸ LEO1 ▸ CDK5 ▸
BMP5 ▸ NOX5 ▸ IL3 ▸ STAT3 ▸ RIPK2 ▸ BMP6 ▸ BMP7 ▸
BMP3 ▸ HSPB1 ▸ PPP2CA ▸ HPR ▸ CD79A ▸ SNAP25 ▸ CARD8 ▸
BMP10 ▸ BMP15 ▸ KRT18 ▸ WDR61 ▸ RAD51 ▸ MST1 ▸ CTR9 ▸
PPP2R1A ▸ PAF1 ▸ IL5 ▸ SMPD2 ▸ APC ▸ PDLIM7 ▸ IL7 ▸
IL33 ▸ IL11 ▸ AGTR1 ▸ TLR5 ▸ NOD1 ▸ TLR7 ▸ RB1 ▸
PRNP ▸ BMP2 ▸ ENDOG ▸ NOX3 ▸ IL24 ▸ PTX3 ▸ CREB5 ▸
GP9 ▸ PTX4 ▸ HIF1A ▸ CDH1 ▸ TXN ▸ JAK2 ▸ RBBP7 ▸
CREB3 ▸ CD4 ▸ ANGPT1 ▸ NPS ▸ SMARCA4 ▸ ACTL6A ▸ CCDC88A ▸
TLR8 ▸ EGFR ▸ CREB1 ▸ WAS ▸ PLCG1 ▸ IGF2 ▸ IL20 ▸
ANGPT2 ▸ ANXA1 ▸ SYK ▸ IL21 ▸ SMARCC1 ▸ SMARCD2 ▸ IL25 ▸
RIPK3 ▸ TLR10 ▸ GP5 ▸ GSN ▸ CXCL9 ▸ BOC ▸ TRAF6 ▸
LMNB2 ▸ GP2 ▸ BIRC6 ▸ TLR1 ▸ SMARCE1 ▸ MET ▸ ABCC6 ▸
PGP ▸ SMARCB1 ▸ ICAM1 ▸ SMARCD1 ▸ TNFRSF1B ▸ LPA ▸ FOXO3 ▸
CSE ▸ IL15 ▸ MAP2K2 ▸ SMARCA2 ▸ RBBP4 ▸ ARID1A ▸ EIF2S1 ▸
CDC6 ▸ GP6 ▸ SMARCC2 ▸ HTT ▸ IL9 ▸ PTEN ▸ KDR ▸
TLR6 ▸ IRF3 ▸ PPARG ▸ TOP1 ▸ SYT1 ▸ IL27 ▸ MUC17 ▸
BECN1 ▸ GATA1 ▸ MEFV ▸ IL32 ▸ IL37 ▸ MSC ▸ IL34 ▸
TLR9 ▸ STX1A ▸ MUC4 ▸ PLD1 ▸ CARD11 ▸ IL26 ▸ CARD9 ▸
BRCA1 ▸ UCN ▸ CCND1 ▸ HMOX1 ▸ RRAS ▸ MUC1 ▸ RAF1 ▸
PRKCA ▸ SMPD1 ▸ ROCK2 ▸ MUC13 ▸ IL13 ▸ RENBP ▸ PAK1 ▸
MUC20 ▸ MUC21 ▸ LYN ▸ MUC6 ▸ SP1 ▸ CDA ▸ ACHE ▸
TRAF1 ▸ IKBKB ▸ CARD6 ▸ MUC8 ▸ IL31 ▸ IL22 ▸ MUC22 ▸
MUC7 ▸ CDK8 ▸ MUC15 ▸ MDM2 ▸ MUC19 ▸ HSPD1 ▸ MUC16 ▸
MUC2 ▸ MUC12 ▸ IL19 ▸ CD79B ▸ H2AFX ▸ IRF4 ▸ CALM3 ▸
HSF1 ▸ PTBP1 ▸ FUT1 ▸ BIRC8 ▸ PLOD2 ▸ DES ▸ PRKAB1 ▸
DERL1 ▸ PEA15 ▸ CTNND1 ▸ SLCO6A1 ▸ HIST2H2BE ▸ WNT1 ▸ CEP128 ▸
IKBKG ▸ GUCY2D ▸ ATF5 ▸ CEP89 ▸ NTF3 ▸ PRKACG ▸ CARD14 ▸
DST ▸ GDNF ▸ PTK2 ▸ PRKCG ▸ CEP104 ▸ CCL2 ▸ ELAVL1 ▸
PRKAR2A ▸ CEP19 ▸ ZGLP1 ▸ E2F1 ▸ PRKAA1 ▸ CARD10 ▸ NPY6R ▸
CEP192 ▸ ME2 ▸ PPP1R3A ▸ HUNK ▸ SETD2 ▸ HSP90AA1 ▸ ARC ▸
EPX ▸ CEP112 ▸ IRF5 ▸ PTHLH ▸ TIMP3 ▸ BIRC5 ▸ CEP41 ▸
MPST ▸ CEP55 ▸ PNPLA2 ▸ CEP170 ▸ PRKAA2 ▸ CARD18 ▸ CEP290 ▸
ATF2 ▸ CEP85 ▸ GRB7 ▸ TRAF3 ▸ MAP2K7 ▸ PRKAG1 ▸ PRKAR1A ▸
WNK1 ▸ CD47 ▸ ALB ▸ CTSL ▸ CEP97 ▸ PRKACB ▸ CEP135 ▸
GRB2 ▸ CEP164 ▸ PIDD ▸ PANX1 ▸ MAP2K5 ▸ SLC9A1 ▸ ALK ▸
PRKAR2B ▸ FOXO1 ▸ NPM1 ▸ LAT ▸ MIF ▸ TARDBP ▸ EHMT1 ▸
IGF1R ▸ CEP72 ▸ ATG5 ▸ VIMP ▸ SOAT1 ▸ PSMD10 ▸ CEP78 ▸
CEP44 ▸ GRB14 ▸ SETBP1 ▸ CEP57 ▸ RASA1 ▸ SEC14L2 ▸ SUB1 ▸
VIM ▸ CARD17 ▸ IRF2 ▸ MAP2K4 ▸ CARD16 ▸ CUL1 ▸ CEP63 ▸
PSEN1 ▸ CD40 ▸ PRKAR1B ▸ MAP2K3 ▸ TNFRSF10A ▸ CEP120 ▸ SKP1 ▸
BACE1 ▸ CEP152 ▸ LYPLA1 ▸ CEP350 ▸ MAP2K6 ▸ PLD2 ▸ CEP250 ▸
BCL2L12 ▸ SLC17A5 ▸ CEP76 ▸ VCP ▸ PRKAB2 ▸ ARSA ▸ CCNH ▸
CEP70 ▸ CEP95 ▸ GRB10 ▸ HIP1 ▸ CDK4 ▸ PRKAG2 ▸ TCHP ▸
CCR7 ▸ ADIPOQ ▸ RAD17 ▸ CEP68 ▸ VDAC1 ▸ TRAF2 ▸ MTX1 ▸
ANP32A ▸ MED7 ▸ PLD4 ▸ CCK ▸ APOE ▸ TAC1 ▸ VDAC2 ▸
WNT3A ▸ CCR3 ▸ HRD ▸ FKBP4 ▸ NTN1 ▸ NUP43 ▸ CCR10 ▸
MED1 ▸ LGALS1 ▸ CDK3 ▸ ATM ▸ FAM168B ▸ PAN3 ▸ SMAD4 ▸
STSP1 ▸ LRRC59 ▸ RIPK4 ▸ TET2 ▸ NLRP7 ▸ HRK ▸ CHUK ▸
ACAD8 ▸ CCL19 ▸ DHCR24 ▸ CDK12 ▸ APOBEC3D ▸ CALR ▸ CDK13 ▸
ABCD1 ▸ MTOR ▸ MED14 ▸ VIP ▸ TFAP2A ▸ IRF9 ▸ ACR ▸
CFTR ▸ SERPINA1 ▸ IFNA2 ▸ MED21 ▸ MED8 ▸ HMGCR ▸ ACSM3 ▸
TMED7 ▸ ETS2 ▸ PSENEN ▸ SREBF2 ▸ GNRH1 ▸ NAB2 ▸ BNIP3 ▸
RAC3 ▸ BCAP31 ▸ IL1RN ▸ PMEL ▸ ITCH ▸ PARG ▸ MME ▸
ANG ▸ EIF4G1 ▸ ERVK-6 ▸ APEX1 ▸ KLF4 ▸ BLM ▸ EEF1A2 ▸
SHC1 ▸ ID3 ▸ TRAF7 ▸ PIN1 ▸ CISH ▸ COP ▸ MICE ▸
DNAJC5 ▸ NLRP5 ▸ ATG3 ▸ NLRC5 ▸ JAK3 ▸ GJA1 ▸ EMP3 ▸
MED6 ▸ PAWR ▸ TET3 ▸ GPI ▸ SERPINF1 ▸ HIPK2 ▸ IFI44 ▸
TRAF5 ▸ NAB1 ▸ DAP3 ▸ DAXX ▸ NUP62 ▸ CPOX ▸ TRAF4 ▸
CDK19 ▸ NOTCH1 ▸ CDK6 ▸ MTA1 ▸ KLK3 ▸ CCR5 ▸ TET1 ▸
TYR ▸ SLPI ▸ RAD1 ▸ PC ▸ PXN ▸ PAEP ▸ TAC4 ▸
MED23 ▸ CAPNS1 ▸ NUP210 ▸ PLK1 ▸ GPX3 ▸ SIVA1 ▸ HTRA1 ▸
E2F3 ▸ FAF1 ▸ HTRA4 ▸ ING1 ▸ E2F2 ▸ EIF4G3 ▸ SREBF1 ▸
SERPINB9 ▸ IFNA5 ▸ C22orf29 ▸ CDK18 ▸ CDK15 ▸ CDCA5 ▸ SATB1 ▸
STX2 ▸ CSF1 ▸ IAPP ▸ DIDO1 ▸ CDK1 ▸ CDK16 ▸ MTA2 ▸
CDC42 ▸ CYR61 ▸ PTH ▸ FHIT ▸ SEPT4 ▸ NAIP ▸ SHH ▸
DYRK1A ▸ APIP ▸ TAC3 ▸ CFL1 ▸ PRG3 ▸ CCNC ▸ CRYAB ▸
CDK14 ▸ IRF8 ▸ HDAC6 ▸ SDS ▸ ETS1 ▸ DLG1 ▸ TGFB3 ▸
RAD52 ▸ XAF1 ▸ CCR4 ▸ ODC1 ▸ CCR8 ▸ RBL2 ▸ NTF4 ▸
MED25 ▸ CCR6 ▸ MTA3 ▸ MT4 ▸ VDAC3 ▸ RAC2 ▸ HTRA3 ▸
MAP3K7 ▸ CXCL13 ▸ EMP2 ▸ NR0B1 ▸ RHO ▸ ACIN1 ▸ PRG2 ▸
SAA1 ▸ JAK1 ▸ CALB1 ▸ XRCC6 ▸ S100A12 ▸ CDK10 ▸ PDGFB ▸
RAD50 ▸ STC1 ▸ EIF4G2 ▸ CDK9 ▸ CTRL ▸ GSTT1 ▸ CDK17 ▸
UCP2 ▸ CTNNBL1 ▸ RUNX3 ▸ GYS2 ▸ NACA ▸ GYS1 ▸ BAG3 ▸
NPPA ▸ SMAD3 ▸ CCR9 ▸ IRS1 ▸ EMP1 ▸ CA8 ▸ MED15 ▸
THBS1 ▸ CD8B ▸ MED17 ▸ HCLS1 ▸ MT3 ▸ PTPN11 ▸ ANXA6 ▸
TNFRSF8 ▸ NODAL ▸ TNFRSF10B ▸ KMT2A ▸ HDAC4 ▸ NUP214 ▸ FLT3 ▸
NANOS2 ▸ TSC22D3 ▸ RAD18 ▸ ADM ▸ NANOG ▸ MED4 ▸ SMAD7 ▸
DAPK2 ▸ CD2 ▸ KLKB1 ▸ CDK7 ▸ MED26 ▸ TRA ▸ TGM2 ▸
EDNRA ▸ GNA11 ▸ TNFSF12 ▸ GPX1 ▸ SPP1 ▸ PAN2 ▸ PTCH1 ▸
GHSR ▸ MST1R ▸ SERP2 ▸ CALML3 ▸ LRP1 ▸ EML2 ▸ NUAK1 ▸
PRG4 ▸ GRP ▸ PLD6 ▸ CIB1 ▸ MAP2 ▸ ADH5 ▸ IRF7 ▸
MED12 ▸ PGF ▸ QRICH2 ▸ ANGPT4 ▸ IDO1 ▸ AIP ▸ CENPK ▸
RAD21 ▸ PLD5 ▸ PSMB9 ▸ IGFBP3 ▸ QRICH1 ▸ AFP ▸ IFIH1 ▸
PPT1 ▸ CCR2 ▸ MED13 ▸ CCR1 ▸ NUP153 ▸ PLD3 ▸ CDK20 ▸
MED24 ▸ RARA ▸ GLI1 ▸ CPA1 ▸ HNRNPA0 ▸ THAP11 ▸ IL1R1 ▸
ACVR1C ▸ RBX1 ▸ MEF2A ▸ CDC2L2 ▸ UNC5B ▸ NUMA1 ▸ NFATC2 ▸
DBNL ▸ UBE4B ▸ PTGES3 ▸ LPAR3 ▸ PIP5K1A ▸ GMNN ▸ ACTA1 ▸
GAS2 ▸ GORASP1 ▸ GZMM ▸ YWHAE ▸ PTMA ▸ KEAP1 ▸ NDUFS1 ▸
TRIM28 ▸ DCTN1 ▸ PRF1 ▸ RABEP1 ▸ MDC1 ▸ COPS6 ▸ BCAR1 ▸
PDE5A ▸ MAP4K1 ▸ AR ▸ BMX ▸ ARHGDIB ▸ PLA2G4A ▸ PSIP1 ▸
FUS ▸ PDE10A ▸ MAP3K14 ▸ SOCS5 ▸ WNK3 ▸ YWHAG ▸ CTTN ▸
PLA2G4B ▸ EIF3J ▸ TNS4 ▸ LPAR1 ▸ DSG2 ▸ NUCB2 ▸ MLH1 ▸
NFE2L2 ▸ ELANE ▸ PPARGC1A ▸ SDC2 ▸ HNRNPD ▸ TP73 ▸ EIF4B ▸
PICALM ▸ ZBTB16 ▸ CD247 ▸ CDC2L1 ▸ PLEKHO1 ▸ AIFM1 ▸ CDK11A ▸
NEO1 ▸ BIRC4 ▸ DSG1 ▸ NMT2 ▸ RNF2 ▸ CAD ▸ TNFRSF25 ▸
AKAP8 ▸ SARS2 ▸ STK24 ▸ DSG3 ▸ NR3C1 ▸ HEY2 ▸ HNRNPU ▸
KARS ▸ EIF3S10 ▸ IQGAP1 ▸ ARHGDIA ▸ GRIPAP1 ▸ FUK ▸ UBC ▸
SAV1 ▸ MAPT ▸ NGFR ▸ PPP3CA ▸ ATN1 ▸ SCAF11 ▸ ATG4D ▸
NGFRAP1 ▸ SYF2 ▸ NVL ▸ FBXW11 ▸ IFT57 ▸ HRAS ▸ IL1R2 ▸
MAPK8IP3 ▸ CDK11B ▸ EIF4A1 ▸
Data information
Please see the Gene Interactions Track Manual.