Gene interactions and pathways from curated databases and text-mining
IL8: top 25 interacting genes
Mouse over or click genes or lines for details. Dashed lines indicate interactions without text mining support. Click any gene to make it the new center. Click any line to show details about the interaction. Only IL8-interacting genes and only the most-mentioned/most-curated interactions are shown in the graph. See the Help Page for details.
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Less-frequently mentioned interactions with IL8, not among the Top 25
Other genes interacting with IL8. Mouse-over to show number of abstracts or databases. Sorted by article count (sort alphabetically).
Like above, interactions are colored by support. Grey:only text mining, light-blue:interaction database, blue:pathway database

TLR4 ▸ TLR2 ▸ FOS ▸ IL4 ▸ IL2 ▸ CSF2 ▸ IL17A ▸
ICAM1 ▸ TLR3 ▸ NM ▸ TLR5 ▸ CD40 ▸ PTGS2 ▸ IL13 ▸
AHSA1 ▸ VEGFA ▸ TLR9 ▸ TLR1 ▸ CA2 ▸ CCL2 ▸ TLR8 ▸
TLR7 ▸ IL3 ▸ RNF19A ▸ IL15 ▸ TLR6 ▸ TLR10 ▸ IL5 ▸
TGFB1 ▸ LTA ▸ IL33 ▸ IL18 ▸ TCF4 ▸ F2RL1 ▸ NOS2 ▸
TCF21 ▸ TCF24 ▸ TCF25 ▸ IL22 ▸ TCF19 ▸ CRK ▸ TCF23 ▸
TCF20 ▸ TCF15 ▸ TCF7 ▸ TCF12 ▸ TCF3 ▸ PIK3CA ▸ NA ▸
CSE ▸ NFKBIA ▸ PIK3R1 ▸ IL32 ▸ MMP9 ▸ LPA ▸ IL1RN ▸
PAF1 ▸ CTR9 ▸ LEO1 ▸ IL31 ▸ GRAP2 ▸ HGF ▸ WDR61 ▸
APOB ▸ CDC73 ▸ EGF ▸ IL11 ▸ CXCR1 ▸ S100A8 ▸ IFNB1 ▸
MMP2 ▸ IL7 ▸ IL25 ▸ ITGAM ▸ IL9 ▸ IL16 ▸ IL21 ▸
IL19 ▸ IL20 ▸ FGF2 ▸ SAA1 ▸ POLDIP2 ▸ MMP3 ▸ IL26 ▸
IL37 ▸ IL34 ▸ IL27 ▸ IL24 ▸ INS ▸ FAS ▸ NOS1 ▸
EGFR ▸ MIF ▸ AKT1 ▸ ALB ▸ CRP ▸ PI3 ▸ AKT3 ▸
CXCR2 ▸ AKT2 ▸ CASP3 ▸ IKBKB ▸ CD14 ▸ NOX1 ▸ MMP13 ▸
MMP1 ▸ CASP4 ▸ CALM3 ▸ CD40LG ▸ CASP14 ▸ NOS3 ▸ CASP6 ▸
CASP2 ▸ CASP10 ▸ CASP16 ▸ CASP12 ▸ CASP5 ▸ CASP1 ▸ NOX4 ▸
CASP9 ▸ CASP8 ▸ F2R ▸ CASP7 ▸ PTX3 ▸ PLG ▸ HMGB1 ▸
NOX5 ▸ NOX3 ▸ PTK7 ▸ CHUK ▸ SELE ▸ IGF1 ▸ NOD1 ▸
PTK6 ▸ LIF ▸ MYLIP ▸ TGFB2 ▸ MYD88 ▸ ITGB2 ▸ TNFSF10 ▸
PTK2 ▸ IFNA2 ▸ SRC ▸ GP2 ▸ PRG2 ▸ MAP3K7 ▸ MUC1 ▸
LEP ▸ STAT3 ▸ MMP8 ▸ PTX4 ▸ PRG3 ▸ TREM1 ▸ GP5 ▸
GP9 ▸ GP6 ▸ CXCL12 ▸ PRG4 ▸ ERVK-6 ▸ IL12B ▸ IKBKG ▸
CRH ▸ VCAM1 ▸ IFNA13 ▸ HNRNPF ▸ LTB ▸ SERPINE1 ▸ MPO ▸
PRKAR1B ▸ MMP14 ▸ VIP ▸ HNRNPH1 ▸ MMP7 ▸ CSF3 ▸ IFNA8 ▸
PRKAR2B ▸ PRKACB ▸ SOD3 ▸ IFNA17 ▸ SOD1 ▸ IFNA21 ▸ PAM ▸
PRKACG ▸ PRKAR1A ▸ PRKAR2A ▸ PTBP2 ▸ IL12A ▸ SOD2 ▸ S100A12 ▸
IFNA10 ▸ IFNA14 ▸ IFNA6 ▸ IFNA16 ▸ HDAC2 ▸ IFNA5 ▸ IFNA7 ▸
PTBP1 ▸ IFNA1 ▸ PLD2 ▸ IFNA4 ▸ WNK1 ▸ MMP25 ▸ IL1R1 ▸
EGR1 ▸ SETD2 ▸ EDN1 ▸ MMP20 ▸ NOD2 ▸ CSK ▸ ELANE ▸
MMP26 ▸ MMP28 ▸ CCL3 ▸ MMP10 ▸ MMP16 ▸ MMP24 ▸ MMP12 ▸
MMP15 ▸ PLD1 ▸ MMP27 ▸ TNFRSF1A ▸ MMP17 ▸ CXCL10 ▸ SPP1 ▸
TGFB3 ▸ HDAC1 ▸ FGF1 ▸ MMP19 ▸ MMP21 ▸ MSH3 ▸ CAT ▸
MMP11 ▸ QRICH2 ▸ PLD6 ▸ SYT1 ▸ PLA2G1B ▸ PLD5 ▸ TAB1 ▸
PLD4 ▸ TRAF6 ▸ CD8A ▸ NAALADL1 ▸ FASLG ▸ MAP2K1 ▸ PLD3 ▸
SST ▸ MSH4 ▸ ANGPT2 ▸ FGF7 ▸ CD4 ▸ QRICH1 ▸ MSH5 ▸
MSH2 ▸ MSH6 ▸ AHR ▸ FGF19 ▸ FGF20 ▸ ADIPOQ ▸ FGF17 ▸
FGF12 ▸ SELL ▸ FGF22 ▸ ETS1 ▸ FGF10 ▸ FGF5 ▸ FGF13 ▸
PDLIM7 ▸ CD38 ▸ FGF8 ▸ ITGB1 ▸ PPARG ▸ FGF14 ▸ HDAC6 ▸
FGF16 ▸ CSF1 ▸ STAT1 ▸ HDAC5 ▸ FGF11 ▸ TXN ▸ C1QB ▸
FGF23 ▸ CD46 ▸ FGF4 ▸ TNFSF12 ▸ FGF6 ▸ FGF3 ▸ CD28 ▸
FGF21 ▸ CSRP1 ▸ HSPD1 ▸ CXCL1 ▸ LTF ▸ HMOX1 ▸ FGF18 ▸
SELP ▸ SOCS3 ▸ HDAC3 ▸ P2RY6 ▸ FGF9 ▸ STX2 ▸ RAC1 ▸
SAA2 ▸ NGF ▸ C1QA ▸ CD8B ▸ PRTN3 ▸ SETBP1 ▸ CD79A ▸
PRKCD ▸ ANGPT1 ▸ GPI ▸ MTX1 ▸ RBBP4 ▸ MUC22 ▸ CPOX ▸
ECM2 ▸ ST8SIA2 ▸ MUC8 ▸ HDAC7 ▸ PDGFB ▸ MUC21 ▸ HDAC9 ▸
MUC20 ▸ PLA2G4A ▸ SAA4 ▸ TNFSF13B ▸ APC ▸ TRPV1 ▸ CXCR3 ▸
MUC2 ▸ AGTR2 ▸ NPS ▸ BCL3 ▸ STAT4 ▸ CFTR ▸ HDAC10 ▸
MUC15 ▸ RBBP7 ▸ PLAU ▸ HDAC11 ▸ TNMD ▸ ITIH4 ▸ CXCR4 ▸
PDCD11 ▸ RHO ▸ MUC4 ▸ MUC19 ▸ TAT ▸ RHOA ▸ HES1 ▸
PF4 ▸ MUC7 ▸ ANG ▸ HDAC4 ▸ CR1 ▸ ECM1 ▸ STX1A ▸
HSPG2 ▸ HDAC8 ▸ MUC16 ▸ MTOR ▸ CISH ▸ NAP1L4 ▸ IL2RA ▸
MUC13 ▸ MUC6 ▸ PPARA ▸ HSPB1 ▸ MUC12 ▸ MUC17 ▸ PRKAB2 ▸
TAC3 ▸ CTNNB1 ▸ UTP6 ▸ IBD6 ▸ PRR7 ▸ PRR19 ▸ ADCYAP1 ▸
IBD3 ▸ ICOSLG ▸ TF ▸ MAP3K1 ▸ ADAM11 ▸ APEX1 ▸ IBD8 ▸
CALM2 ▸ JAK2 ▸ PAEP ▸ LPL ▸ PRR4 ▸ PRKAG2 ▸ PTAFR ▸
BCL10 ▸ PRR21 ▸ PRKAB1 ▸ ICAM3 ▸ HES3 ▸ DEFA1 ▸ IL17F ▸
MPL ▸ PRR11 ▸ RENBP ▸ CXCL11 ▸ IRAK3 ▸ HES5 ▸ MET ▸
DUSP1 ▸ TP53 ▸ CYP1A1 ▸ UTP18 ▸ SEA ▸ SIGLEC7 ▸ EMD ▸
PGF ▸ ELF3 ▸ IBD4 ▸ PRL ▸ OSM ▸ TAC4 ▸ FGA ▸
UTP20 ▸ RELB ▸ IL1R2 ▸ MAP2K7 ▸ PGD ▸ HDC ▸ PRR18 ▸
NR0B1 ▸ UTP15 ▸ CXCL6 ▸ PRDX2 ▸ ETS2 ▸ EPO ▸ IBD5 ▸
HES7 ▸ BCL2 ▸ FCGR1A ▸ ROCK2 ▸ MT3 ▸ PRR12 ▸ PRR9 ▸
TGFA ▸ IBD2 ▸ PRR14 ▸ GRP ▸ ICAM5 ▸ NR4A2 ▸ SELPLG ▸
CALM1 ▸ ICAM2 ▸ PRR13 ▸ PRKCA ▸ FGG ▸ ARG2 ▸ RNASE3 ▸
TFPI ▸ AZU1 ▸ FOXO3 ▸ UTP3 ▸ MT4 ▸ HES4 ▸ IRAK1 ▸
CCR5 ▸ PRR25 ▸ IBD7 ▸ ICAM4 ▸ PRR15 ▸ PRKAA1 ▸ PKD1 ▸
NTS ▸ UTP23 ▸ ESR1 ▸ PRR16 ▸ PRR5 ▸ ADAM17 ▸ IBD9 ▸
CXCL17 ▸ TAC1 ▸ BRAF ▸ PRKAA2 ▸ PRR3 ▸ A2M ▸ DDIT3 ▸
NUP43 ▸ TPO ▸ ARG1 ▸ HES6 ▸ MUC5AC ▸ PRKAG1 ▸ HBEGF ▸
CHI3L1 ▸ HES2 ▸ CCL20 ▸ IFI44 ▸ ELF4 ▸ SMAD3 ▸ PRR26 ▸
CXCL9 ▸ PRR22 ▸ PRR24 ▸ AREG ▸ CPB2 ▸ GAL ▸ HMGB4 ▸
FUT9 ▸ RNASE2 ▸ NPY4R ▸ POU2F1 ▸ ADAM10 ▸ CD1D ▸ CD44 ▸
HCG24 ▸ MTA3 ▸ CAPN9 ▸ CXCL3 ▸ BPI ▸ DEFA1B ▸ ADAM19 ▸
F2RL2 ▸ CEBPB ▸ SYK ▸ HCG17 ▸ DPM2 ▸ F10 ▸ SPP2 ▸
DPM1 ▸ CEBPA ▸ ALX1 ▸ SCARB1 ▸ CAPN8 ▸ CCL5 ▸ HCG21 ▸
UCN2 ▸ GRB14 ▸ DDX58 ▸ MYO6 ▸ PTPN11 ▸ CD83 ▸ IDO1 ▸
FGFR2 ▸ HCG4 ▸ HCG11 ▸ HCG22 ▸ NAMPT ▸ WNT6 ▸ RABEPK ▸
SMAD5 ▸ REL ▸ CD69 ▸ SMAD9 ▸ FCER2 ▸ JAK3 ▸ MEFV ▸
FOXO1 ▸ HMGB3 ▸ VCP ▸ FOSL1 ▸ GSTM1 ▸ ELAVL1 ▸ PAK1 ▸
SPESP1 ▸ HCG26 ▸ GRB10 ▸ FUT4 ▸ ACKR3 ▸ CEACAM6 ▸ IFIH1 ▸
ADM ▸ BCL6 ▸ ALX4 ▸ ALOX5 ▸ MAP2K3 ▸ NR4A1 ▸ PTHLH ▸
ABL1 ▸ DNASE1 ▸ TMSB4X ▸ FUT5 ▸ FUT8 ▸ MAP2K5 ▸ SMAD7 ▸
FOXO6 ▸ SLPI ▸ CXCL14 ▸ CD163 ▸ HCG15 ▸ MAPKAPK2 ▸ CAPN7 ▸
CNR2 ▸ DUOX1 ▸ GH1 ▸ GHRH ▸ MAP2K4 ▸ TPT1 ▸ GRPR ▸
IL23A ▸ FUT6 ▸ ELF1 ▸ PTGS1 ▸ TBP ▸ NPY ▸ FMR1 ▸
CD2 ▸ RETN ▸ BCR ▸ CDH5 ▸ WNT16 ▸ TNFSF11 ▸ CAPN5 ▸
CNR1 ▸ CTSB ▸ CPB1 ▸ PARK7 ▸ VASP ▸ AGTR1 ▸ HCG25 ▸
HCG16 ▸ MAP2K6 ▸ CXCL16 ▸ CXCL2 ▸ FUT2 ▸ CCL4 ▸ PARK2 ▸
CAPN15 ▸ PAK3 ▸ SERPINB2 ▸ ALX3 ▸ FUT3 ▸ HBD ▸ FOXO4 ▸
VAV1 ▸ PAK6 ▸ C1orf228 ▸ ELF2 ▸ MKNK1 ▸ RAG1 ▸ HCG9 ▸
CDC42 ▸ APOA2 ▸ THBD ▸ APOE ▸ CSTA ▸ CTGF ▸ FUT10 ▸
PINK1 ▸ HCG14 ▸ CDH1 ▸ FUT1 ▸ TRAF2 ▸ CAPN11 ▸ HRH1 ▸
HCG27 ▸ RAC3 ▸ APOA1 ▸ IGF2 ▸ PITX1 ▸ CAPN14 ▸ PTPN22 ▸
PAK7 ▸ CSH1 ▸ CXCL13 ▸ HIF1A ▸ VDR ▸ TNP2 ▸ FXYD1 ▸
TNFRSF9 ▸ WNT11 ▸ CEACAM1 ▸ KSR2 ▸ SMAD4 ▸ MTA1 ▸ HCG23 ▸
WNT1 ▸ ANPEP ▸ CAPN13 ▸ TNFRSF1B ▸ F7 ▸ HRAS ▸ PAK4 ▸
CAPN3 ▸ MYO16 ▸ TACR1 ▸ SOAT1 ▸ KLK3 ▸ MYO19 ▸ FUT7 ▸
JAK1 ▸ RAC2 ▸ GRB7 ▸ ASIP ▸ ELF5 ▸ HCG18 ▸ CSH2 ▸
ITGA5 ▸ GAST ▸ MYO10 ▸ HMGB2 ▸ BLM ▸ MPG ▸ FUT11 ▸
HCG8 ▸ CAPN6 ▸ IRS1 ▸ CGN ▸ SMAD2 ▸ KDR ▸ CTSS ▸
CX3CL1 ▸ TNPO1 ▸ MEPE ▸ TEC ▸ TSC22D3 ▸ NLRP3 ▸ MTA2 ▸
TRNAI1 ▸ C3 ▸ CAPN1 ▸ DNASE2 ▸ CA1 ▸ ARSA ▸ WNT4 ▸
CYP19A1 ▸ AR ▸ PAH ▸ PDGFA ▸ ATP8A2 ▸ NFKBIZ ▸ PAK2 ▸
SERPINE2 ▸ HCG20 ▸ OXA1L ▸ SFXN1 ▸ FCGR2B ▸ NPY6R ▸ DPM3 ▸
KLRB1 ▸ PROK1 ▸ PDCD4 ▸ CAPN12 ▸ CAPN2 ▸ ROCK1 ▸ BMP2 ▸
WNT2 ▸ WNT3 ▸ LBP ▸ CXCL5 ▸ STAT5A ▸ CYP1A2 ▸ S100A9 ▸
CAPN10 ▸ GRB2 ▸ CP ▸ CXCR6 ▸ MRXS5 ▸ HLA-DRB1 ▸ KRT10 ▸
SMAD1 ▸ GIP ▸ FGB ▸ MBP ▸ TNP1 ▸ MAP2K2 ▸ PGP ▸
CD86 ▸ FOXP3 ▸ SMAD6 ▸ GRM2 ▸ OXGR1 ▸ CCR4 ▸ CCL25 ▸
GRM7 ▸ GPER1 ▸ PNOC ▸ BDKRB2 ▸ PTGER3 ▸ HTR1B ▸ GALR2 ▸
GALR3 ▸ S1PR2 ▸ TAS2R1 ▸ TAS2R39 ▸ SSTR2 ▸ ADORA3 ▸ GABBR2 ▸
HTR1A ▸ NMUR2 ▸ CCR6 ▸ GNAI3 ▸ S1PR3 ▸ P2RY13 ▸ HTR1F ▸
FPR1 ▸ HRH3 ▸ TAS2R45 ▸ CCL28 ▸ TAS2R46 ▸ CCL27 ▸ ADRA2C ▸
NPY5R ▸ GRM8 ▸ PMCH ▸ CHRM4 ▸ PENK ▸ GNAI1 ▸ NPY2R ▸
P2RY12 ▸ C3AR1 ▸ CCR8 ▸ TAS2R5 ▸ CCR7 ▸ TAS2R43 ▸ RXFP3 ▸
NMUR1 ▸ CCR1 ▸ PDYN ▸ ANXA1 ▸ OPRL1 ▸ TAS2R40 ▸ NPY1R ▸
TAS2R9 ▸ LPAR5 ▸ GALR1 ▸ GABBR1 ▸ CCR9 ▸ TAS2R3 ▸ DRD4 ▸
SSTR5 ▸ DRD3 ▸ CCR10 ▸ RXFP4 ▸ TAS2R38 ▸ TAS2R42 ▸ GNAI2 ▸
GRM3 ▸ TAS2R8 ▸ HCAR1 ▸ CCL16 ▸ NPBWR1 ▸ SSTR3 ▸ TAS2R7 ▸
MTNR1A ▸ SSTR1 ▸ CCL19 ▸ ADORA1 ▸ TAS2R16 ▸ TAS2R14 ▸ S1PR1 ▸
TAS2R30 ▸ HTR1E ▸ GNG2 ▸ PYY ▸ HCAR2 ▸ TAS2R4 ▸ DRD2 ▸
PTGDR2 ▸ GNAT3 ▸ CCR2 ▸ TAS2R60 ▸ GNB1 ▸ OPRD1 ▸ SUCNR1 ▸
NPBWR2 ▸ DARC ▸ P2RY4 ▸ CX3CR1 ▸ GRM6 ▸ MCHR1 ▸ NMU ▸
OPRK1 ▸ U2AF1 ▸ APLNR ▸ TAS2R31 ▸ ADRA2A ▸ HEBP1 ▸ KNG1 ▸
HCAR3 ▸ MT-RNR2 ▸ SSTR4 ▸ INSL5 ▸ S1PR4 ▸ NPB ▸ HRH4 ▸
S1PR5 ▸ OXER1 ▸ TAS2R19 ▸ ADRA2B ▸ TAS2R41 ▸ HTR5A ▸ TAS2R10 ▸
TAS2R20 ▸ GRM4 ▸ PPBP ▸ C5AR1 ▸ BDKRB1 ▸ PPY ▸ TAS2R13 ▸
FPR3 ▸ TAS2R50 ▸ HTR1D ▸ MCHR2 ▸ CHRM2 ▸ XCR1 ▸ MTNR1B ▸
Data information
Please see the Gene Interactions Track Manual.