Gene interactions and pathways from curated databases and text-mining

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CASP3 — MTX1

Text-mined interactions from Literome

Yang et al., Biochem Pharmacol 2011 : MTX induced marked apoptotic changes in immature hippocampal cells, with increase in active caspase-3 and cleaved poly ( ADP-ribose ) polymerase expressions
Tsai et al., Cell death & disease 2013 (Carcinoma, Squamous Cell...) : MTX increased WWOX expression, accompanied by caspase activation and apoptosis, in MTX-sensitive SCC cell lines and tumor biopsies