◀ Back to GRAP2
GRAP2 — MAPKAPK2
Text-mined interactions from Literome
Platanias et al., Pharmacol Ther 2003
(Leukemia, Myelogenous, Chronic, BCR-ABL Positive) :
The activated form of
p38 regulates downstream activation of other serine kinases, notably
MapKapK-2 and MapKapK-3, indicating the existence of Type I IFN dependent signaling cascades activated downstream of p38
Hu et al., J Biol Chem 2006
(MAP Kinase Signaling System) :
MAPKAPK-2 , Akt2, and ezrin phosphorylation were all
attenuated by
p38 MAPK inhibition but were unaffected by dominant negative ezrin expression
Gorog et al., Cell Stress Chaperones 2009
(Myocardial Ischemia) :
p38-MAPK activation is thought to contribute to myocardial ischemic injury ; therefore, we investigated
MK2 effects on ischemic injury and
p38 cellular localization using MK2-deficient mice ( KO )
Hendriks et al., BMC systems biology 2010
:
We found that in a dual ( MK2 and ATF2 ) substrate assay,
MK2-p38 interaction
reduced the activity of
p38 against ATF2
Marshall et al., J Immunol 1998
:
IL-4 induced a late ( > 4-h ) increase in
p38 MAPK activity and corresponding
activation of its substrate
MAPKAPK-2