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CTNNB1 — MMP8

Text-mined interactions from Literome

Mei et al., Carcinogenesis 2002 : These MMP inhibitors also blocked the cytosolic accumulation of beta-catenin and nuclear formation of beta-catenin/LEF-1 complex
Kong et al., Cancer Res 2004 (Fibroma...) : Because beta-catenin can regulate MMP expression, we investigated the expression of several MMPs and TIMPs in aggressive fibromatosis tumors that develop in Apc+/Apc1638N mice
Tamamura et al., J Biol Chem 2005 : Delta-beta-catenin expression markedly increased expression of MMP-2, MMP-3 , MMP-7, MMP-9, MT3-MMP, and ADAMTS5
Shibata et al., Int J Oncol 2009 (Carcinoma, Squamous Cell...) : TGFbeta1 dependent, MMP7 mediated up-regulation of beta-catenin/LEF1 signaling and TGFbeta1 activated HMGA2 pathways consequently converged with Slug overexpression, due to disassembly and further repression of E-cadherin expression, which was reproducible in the epithelial mesenchymal transition process without any manipulation
Garg et al., Cancer Res 2010 (Colitis...) : Despite being a mediator of proinflammatory responses in colitis, MMP-9 plays a protective role and acts as a tumor suppressor in CAC by modulating Notch-1 activation, thereby resulting in activation of p21 ( WAF1/Cip1 ) and suppression of beta-catenin
Arozarena et al., Oncogene 2011 (Colonic Neoplasms...) : Downstream of beta-catenin MITF not only suppresses the Rho-GTPase regulated cell morphology of invading melanoma cells, but also interferes with beta-catenin induced expression of the essential collagenase MT1-MMP , thus affecting all aspects of an invasive phenotype