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CCL17 — TNF

Text-mined interactions from Literome

Ju et al., Biochem Biophys Res Commun 2009 : Keratinocytes, one of major cell types in the skin, can be induced by TNF-alpha and IFN-gamma to express thymus- and activation regulated chemokine ( TARC/CCL17 ), which is considered to be a pivotal mediator in the inflammatory responses during the development of inflammatory skin diseases, such as atopic dermatitis ( AD )
Choi et al., Arch Pharm Res 2010 : Interestingly, PC significantly suppressed IFN-gamma and TNF-alpha induced TARC/CCL17 , MDC/CCL22 and CTACK/CCL27 expression via the induction of heme oxygenase (HO)-1 ... Furthermore, exogenous CO, but not other end products of HO-1 activity, also suppressed IFN-gamma and TNF-alpha induced TARC/CCL17 , MDC/CCL22 and CTACK/CCL27 expression
Shibata et al., Vet Immunol Immunopathol 2011 : Identification of the signaling pathway of TNF-a induced CCL17/TARC transcription in a canine keratinocyte cell line ... The aim of the present study is to clarify the regulatory mechanism of TNF-a induced CCL17 mRNA transcription in canine keratinocytes leading to the development of a chemokine targeted therapy for cAD ... The present results suggest that TNF-a induced CCL17 mRNA transcription in CPEK is positively regulated by p38 but negatively controlled by ERK
Jung et al., Biochem Biophys Res Commun 2012 (Dermatitis, Atopic) : In present study, we investigated the effect of spinasterol-Glc on production of TARC/CCL17 induced by TNF-a and IFN-? in human HaCaT keratinocytes ... Spinasterol-Glc inhibited the mRNA and protein expression of TARC/CCL17 induced by TNF-a/IFN-? in a dose dependent manner ... Inhibitors of c-Raf-1, p38 MAPK, and JAK2, suppressed the TNF-a/IFN-? induced production of TARC/CCL17 , and phosphorylation of these signaling molecules were attenuated by spinasterol-Glc