Gene interactions and pathways from curated databases and text-mining

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AKT3 — HSPD1

Text-mined interactions from Literome

Lai et al., Am J Physiol Endocrinol Metab 2007 (Diabetes Mellitus, Experimental) : In the mitochondria depleted cells, overexpression of HSP60 with adenoviral vector increased the abundance of IGF-I receptor, enhanced IGF-I activated receptor phosphorylation, and augmented IGF-I activation of Akt and ERK
Wang et al., Bone 2011 (Osteoporosis) : HSP60 gene transfer activated ERK and Akt and reduced Bax and cytochrome c release, as well as caspase-3 cleavage, which attenuated the inhibitory effects of glucocorticoid treatment on osteoblast survival