Gene interactions and pathways from curated databases and text-mining

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AGTR2 — AKT1

Text-mined interactions from Literome

Cui et al., Mol Endocrinol 2002 : Moreover, we demonstrated that AT2 receptor stimulation inhibited insulin induced Akt phosphorylation and that insulin mediated antiapoptotic effect was also blocked by AT2 receptor activation
Caruso-Neves et al., Proc Natl Acad Sci U S A 2005 : Taken together, these data show that Ang II increases albumin endocytosis through an AT(2) receptor mediated by activation of PKB in the plasma membrane, which depends on the basal activity of the phosphatidyl-inositol 3-kinase