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AGTR2 — MAPK12

Text-mined interactions from Literome

Zimpelmann et al., American journal of physiology. Renal physiology 2001 : In summary, AT(2) receptors in proximal tubule cells inhibit MAPK activity and stimulate phosphotyrosine phosphatase
Sekine et al., Arch Biochem Biophys 2003 : AT II also activated the extracellular signal regulated kinase ( ERK ) and p38 MAPK in the presence of AT II
Kumar et al., J Cardiovasc Pharmacol Ther 2003 (Disease Models, Animal...) : Our aim was to assess the effect of selective AT1 and AT2 receptor blockade with losartan and PD123,319, respectively, on MAPK expression after ischemia-reperfusion in isolated working rat hearts
Hayashida et al., J Biol Chem 1996 : The antagonistic effect of the AT2-3LP on mitogen activated protein kinase activity and DNA synthesis were reversed by pertussis toxin and sodium orthovanadate
Shenoy et al., Endocrinology 1999 : Concurrent activation of c-Jun N-terminal kinase (JNK) and inhibition of Erk mitogen activated protein kinase activities is important for apoptosis in many cells, and we previously demonstrated that stimulation of AT2 receptors causes decreased mitogen activated protein kinase activity in neurons cultured from newborn rat hypothalamus and brain stem
McNeill et al., Endocr Res 1998 : Therefore, MAPK is located in the glomerulosa, where the AT1 receptor is localised and concerned with aldosterone biosynthesis, and in the medulla where MAPK activation results from AT2R activation