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ALB — TNF
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Ngai et al., Pediatr Res 1999
(Glioblastoma...) :
The horseradish peroxidase oxidation method was applied for bilirubin-albumin titration studies to test the
effect of endotoxin and
TNF-alpha on
bilirubin-albumin binding
Li et al., Zhonghua Wai Ke Za Zhi 1997
(Hypoproteinemia...) :
Endotoxin
inhibited albumin mRNA expression in vivo probably by stimulating
TNF , IL-1, and IL-6 production
Buck et al., EMBO J 2001
(Cachexia) :
Hepatic cells expressing the non-phosphorylatable C/EBPbeta alanine mutant were refractory to the inhibitory
effects of
TNF-alpha on
albumin transcription since the mutant remained localized to the nucleus
Fan et al., Arch Biochem Biophys 2003
:
Methylglyoxal-bovine serum
albumin stimulates
tumor necrosis factor alpha secretion in RAW 264.7 cells through activation of mitogen activating protein kinase, nuclear factor kappaB and intracellular reactive oxygen species formation ... Our findings suggest that the presence of chronically elevated levels of MGO modified bovine serum
albumin may
contribute to elevated levels of
TNFalpha in diabetes
Meiners et al., J Neural Transm 2004
:
We show that chicken egg
albumin-AGEs prepared with glucose and chicken egg albumin-AGEs prepared with methylglyoxal dose-dependently
induce TNF-alpha release
Kowalski-Saunders et al., Hepatology 1992
:
Pure interleukin-1, interleukin-6 and
tumor necrosis factor-alpha also
inhibited albumin synthesis ( p less than 0.05, Wilcoxon 's rank sum test, n = 5 ), interleukin-6 having the greatest effect
Smolarczyk et al., Cytokine 2005
:
Negligible
induction of IFN-gamma, IL-12 and
TNF-alpha by DNA-PEI 750
kDa/albumin complexes
Tasaka et al., Am J Respir Cell Mol Biol 2005
(Pulmonary Edema...) :
Tumor necrosis factor-alpha significantly
increased albumin transfer, which was attenuated by pretreatment with Y-27632
Rashid et al., Isr Med Assoc J 2006
:
To investigate the
effect of AGE modified 132m and AGE-human serum
albumin on
TNF-alpha and IL-1beta secretion by human peritoneal macrophages derived from patients on continuous ambulatory peritoneal dialysis
Ibrahim et al., Am J Pathol 2011
(Diabetic Retinopathy) :
The results showed that activation of A ( 2A ) AR attenuated Amadori glycated
albumin induced
TNF-a release in a cAMP/exchange protein directly activated by cAMP dependent mechanism and significantly repressed the inflammatory cascade, C-Raf/extracellular signal regulated kinase ( ERK ), in activated microglia
Brenner et al., J Clin Invest 1990
(Cachexia...) :
Tumor necrosis factor-alpha inhibits
albumin gene expression in a murine model of cachexia ... Since tumor necrosis factor-alpha (TNF alpha) is elevated in cachexia associated diseases, and chronic administration of TNF alpha induces cachexia in animal models, we assessed the
regulation of
albumin gene expression by
TNF alpha in vivo ... Therefore,
TNF alpha selectively
inhibits the genetic expression of
albumin in this model before weight loss
Nishikawa et al., J Cell Biochem 2013
(Drug-Induced Liver Injury, Chronic...) :
Among the cytokines examined,
tumor necrosis factor (TNF)-a inhibited expression of
albumin and HNF-4a, both at mRNA and protein levels
Hamilton et al., J Immunol 1990
:
The expression of maleyl
albumin stimulated
TNF-alpha mRNA expression could be reproduced by lipid extracts of oxidized LDL provided to macrophages at the same cholesterol concentration as from the intact lipoprotein particle
Perlmutter et al., J Clin Invest 1986
(Carcinoma, Hepatocellular...) :
In picomolar concentrations,
TNF mediated reversible, dose- and time dependent increases in biosynthesis of complement proteins factor B and C3, alpha 1 antichymotrypsin, and decreases in biosynthesis of
albumin and transferrin in human hepatoma cell lines ( Hep G2, Hep 3B )
Magielska-Zero et al., Biochem Int 1988
(Carcinoma, Hepatocellular...) :
Human recombinant
tumor necrosis factor only slightly
affects production of alpha 1-antichymotrypsin and
albumin in a similar manner as leukocyte cytokines
Haranaka et al., Tohoku J Exp Med 1984
(Mammary Neoplasms, Experimental) :
Free lipid A and lipid A-mouse serum
albumin complex, which were prepared from the acid hydrolyzate, effectively
induced TNF
Salazar et al., Biochim Biophys Acta 1995
:
The binding of short-term glycated
albumin to MonoMac 6 cells
induced the production of the cytokines IL-1 and
TNF
Yasui et al., Chem Pharm Bull (Tokyo) 1993
:
Cryoprotective
effect of gelatin and
albumin on recombinant human
tumor necrosis factor liposome
Dahn et al., Metabolism 1994
:
Effects of
tumor necrosis factor-alpha on glucose and
albumin production in primary cultures of rat hepatocytes
Hennig et al., J Nutr 1993
:
The lower concentration of Zn partially and the higher concentration totally prevented the
tumor necrosis factor induced increase in
albumin transfer
Amore et al., Kidney Int 1997
:
Glycated
albumin induced increased mRNA expression and synthesis of
TNF-alpha
Abordo et al., Immunol Lett 1997
:
Human serum
albumin minimally modified by methylglyoxal ( MGmin-HSA )
stimulated the synthesis and secretion of
tumour necrosis factor-alpha (TNF-alpha) from human monocytic THP-1 cells in vitro ... Human serum
albumin minimally modified by glucose derived advanced glycation endproducts ( AGEmin-HSA ) and human serum albumin highly modified by glucose derived advanced glycation endproducts ( AGE-HSA )
stimulated markedly lower synthesis and secretion of
TNF-alpha from THP-1 cells than did MGmin-HSA