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APLP2 — APP

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Dip Interaction: Complex of APLP2-APLP1-APP (anti bait coimmunoprecipitation) Wang et al., Proc Natl Acad Sci U S A 2007*
• IRef Intact Interaction: APLP2 — APP (direct interaction, anti tag coimmunoprecipitation) Soba et al., EMBO J 2005*
• IRef Intact Interaction: APLP2 — APP (physical association, anti tag coimmunoprecipitation) Soba et al., EMBO J 2005*

Text-mined interactions from Literome

Bayer et al., Mol Psychiatry 1999 (Alzheimer Disease) : In normal adult brain APP , APLP1 and APLP2 are involved in synaptic processes important for memory function
Araki et al., Brain Res Mol Brain Res 1998 (Alzheimer Disease) : Total APP mRNA levels increased gradually after 24 h, reaching levels 250 % higher than those in control cells at 48 h after NGF withdrawal, and total APLP2 mRNA levels also increased similarly at 48 h. Analysis of the three major APP mRNA isoforms APP695, APP751, and APP770 by reverse transcription polymerase chain reaction showed a substantial increase in the proportion of APP770 at 48 h after NGF withdrawal