Gene interactions and pathways from curated databases and text-mining

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ARC — VWF

Text-mined interactions from Literome

Mayr et al., Transfusion 2010 (Purpura, Thrombotic Thrombocytopenic) : ARC1779 potently and specifically inhibits VWF activity and VWF dependent PLT function
Jilma-Stohlawetz et al., Thromb Haemost 2012 (Thrombocytopenia...) : Thus, we hypothesised that ARC1779 may increase VWF levels and correct thrombocytopenia ... In conclusion, ARC1779 markedly increases VWF/FVIII levels and most importantly improves or even corrects thrombocytopenia in VWD type 2B patients