Mayr et al., Transfusion 2010
(Purpura, Thrombotic Thrombocytopenic) :
ARC1779 potently and specifically inhibits VWF activity and VWF dependent PLT function
Jilma-Stohlawetz et al., Thromb Haemost 2012
(Thrombocytopenia...) :
Thus, we hypothesised that ARC1779 may increase VWF levels and correct thrombocytopenia ... In conclusion, ARC1779 markedly increases VWF/FVIII levels and most importantly improves or even corrects thrombocytopenia in VWD type 2B patients