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ATP7A — TNF
Text-mined interactions from Literome
Buxadé et al., Immunity 2005
(MAP Kinase Signaling System) :
A selective
Mnk inhibitor or siRNA mediated knockdown of Mnk1
inhibits TNFalpha production in T cells, whereas Mnk1 overexpression enhances expression of a reporter construct containing the TNFalpha 3'UTR
Fukunaga et al., EMBO J 1997
:
Further,
MNK1 was activated upon
stimulation of HeLa cells with 12-O-tetradecanoylphorbol-13-acetate, fetal calf serum, anisomycin, UV irradiation,
tumor necrosis factor-alpha , interleukin-1beta, or osmotic shock, and the activation by these stimuli was differentially inhibited by the MEK inhibitor PD098059 or the p38 MAP kinase inhibitor SB202190