Gene interactions and pathways from curated databases and text-mining

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BAX — HDAC1

Text-mined interactions from Literome

Suzuki et al., Int J Cancer 2000 (Mouth Neoplasms...) : TSA enhanced the protein expression of p21 ( WAF1 ), CREB binding protein, cyclinE, cyclin A, Bak and Bax , while it reduced the expression of E2F-1, E2F-4, HDAC1 , p53 and hyperphosphorylated form of Rb
GarcĂ­a-Morales et al., Mol Cancer Ther 2005 (Adenocarcinoma...) : Initially, histone deacetylase inhibitors increase Bax protein levels without affecting Bcl-2 levels