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BBS2 — CA2

Text-mined interactions from Literome

Törnquist et al., Endocrinology 1991 : Pretreatment of the cells with 1 nM 1,25- ( OH ) 2D3 for 24 h enhanced the BBS induced transient increase in [Ca2+ ] i compared to that in control cells, while having no significant effect on the plateau phase of [Ca2+ ] i. Addition of the Ca2+ channel blocker nimodipine or chelating extracellular Ca2+ with EGTA did not abolish the enhancement of the BBS response in 1,25- ( OH ) 2D3 pretreated cells ... Furthermore, the BBS induced efflux of 45Ca2+ from cells preequilibrated with 45Ca2+ was larger in cells treated with 1,25- ( OH ) 2D3
Hirai et al., Life Sci 1993 (Colonic Neoplasms) : Increases in intracellular Ca2+ ( [ Ca2+ ] i ) levels mediated by bombesin (BBS) are believed to be important signals leading to stimulation of DNA synthesis and an increase in cellular proliferative rate ... We also examined the effect of BBS on intracellular Ca2+ levels to determine if the growth-regulatory effect of BBS is mediated through increases in [Ca2+ ] i. Levels of [Ca2+ ] i in response to BBS were measured by single cell fluorescence after loading with fura-2 ... These findings suggest that the BBS mediated increase in [Ca2+ ] i does not always correlate with the growth-regulatory effect of BBS
Imoto et al., Res Commun Mol Pathol Pharmacol 1996 (Glioma) : The addition of verapamil, diltiazem and nimodipine did not affect an increase in [ Ca2+ ] i induced by BBS and TG