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AKT1 — CA2

Text-mined interactions from Literome

Takahashi et al., Am J Physiol 1999 : Akt/PKB activity was stimulated by the Ca2+ ionophore ionomycin, suggesting the possible involvement of Ca2+ in ANG II-stimulated Akt/PKB activation
Egea et al., J Cell Biol 2001 : In this report, we have analyzed the involvement of Ca2+ and calmodulin (CaM) in the activation of the PKB induced by NTs
Tang et al., J Biol Chem 2002 (Astrocytoma...) : Muscarinic receptors mediate phospholipase C-dependent activation of protein kinase B via Ca2+ , ErbB3, and phosphoinositide 3-kinase in 1321N1 astrocytoma cells
Spicer et al., Endocr Pathol 2003 : Research over the last few years has revealed that the hypoxia response in PC12 cells involves the interactions of several signal transduction pathways ( Ca2+/calmodulin dependent kinases, Akt , SAPKs, and MAPKs ) and transcription factors ( HIFs, CREB, and c-fos/junB )
Crossthwaite et al., J Neurochem 2004 : We have previously shown that Ca2+-influx through NMDA receptors in cultured striatal neurones mediates the phosphorylation of extracellular signal regulated kinase 1/2 ( ERK1/2 ) and Akt/protein kinase B (PKB) through a phosphatidylinositol 3-kinase ( PI 3-kinase ) -dependent pathway
Ozeki et al., Mol Cell Biochem 2004 (Calcium Signaling) : However, it is not known if activation of Akt is itself involved in the regulation of Ca2+ signals produced in these cells ... The objective of this study was to examine if Akt is involved in the regulation of Ca2+ signaling in endothelial cells ... Agonist stimulated Ca2+ signals, assessed using fura-2, were compared in porcine aortic endothelial cells under control conditions or conditions in which Akt was blocked either by different inhibitors of phosphatidylinositol 3-kinase ( PI3 kinase ) /Akt or by transient expression of a dominant negative form of Akt ( dnAkt ) ... We conclude that Akt is not involved in the regulation of agonist stimulated Ca2+ signals in endothelial cells
Yasuoka et al., J Biol Chem 2004 : Antiapoptotic activity of Akt is down-regulated by Ca2+ in myocardiac H9c2 cells
Evans et al., J Biol Chem 2006 : Secretory stimuli in both intact and permeabilized cells induced Akt phosphorylation on serine 473, and the time course of Ca2+ induced Akt phosphorylation was similar to that of exocytosis in permeabilized cells
Yamaguchi et al., J Am Soc Nephrol 2006 (Polycystic Kidney Diseases...) : Elevation of intracellular Ca2+ levels in ADPKD cells increased Akt activity and blocked cAMP dependent B-Raf and ERK activation
Catalucci et al., J Cell Biol 2009 (Calcium Signaling...) : Akt regulates L-type Ca2+ channel activity by modulating Cavalpha1 protein stability