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CA2 — CASR
Text-mined interactions from Literome
Gilster et al., Dig Dis Sci 2004
:
In a previous study, we found the existence of a
CaSR which was
activated by extracellular
Ca2+ and found to increase intracellular Ca2+ [Ca2+ ] i, MAP-kinase activity, and gastric epithelial cell proliferation
Bhagavathula et al., Br J Cancer 2005
(Carcinoma...) :
A clonal isolate of the CBS line that did not upregulate
CaSR expression in
response to extracellular
Ca2+ was isolated from the parent cells
Nam et al., Exp Mol Med 2006
(Calcium Signaling) :
Characterization of the compound in a cell based system revealed that an extracellular
calcium sensing receptor (CaSR)- mediated cADPR production and a later long lasting increase in intracellular
Ca2+ concentration ([Ca2+]i) in mouse mesangial cells were
inhibited by the pre-treatment with this compound
Li et al., J Biomed Sci 2011
:
CaSR is expressed in rat PASMCs, and is
involved in regulation of PA tension by increasing [
Ca2+ ] i through G-PLC-IP3 pathway
Kong et al., Biochim Biophys Acta 2012
:
We conclude that the external Ca2+ concentration plays an important role in the regulation of the basolateral K channel activity in the TAL and that the effect of the external
Ca2+ is
mediated by the
CaSR which stimulates PLC-PKC pathways
Gama et al., J Biol Chem 1998
:
A carboxyl-terminal domain controls the cooperativity for extracellular
Ca2+ activation of the human
calcium sensing receptor