Gene interactions and pathways from curated databases and text-mining

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APP — CAST

Text-mined interactions from Literome

Yoon et al., Neuroreport 2007 (Alzheimer Disease...) : We also show that the mint-1 and mint-2 cleavage and APP overexpression were prevented by calpain inhibitor-I and inhibitor-II
Morales-Corraliza et al., Neurobiol Aging 2012 : This CAST dependent decrease in APP metabolite levels was not observed in single tg CAST mice expressing endogenous APP or in younger, Aß plaque predepositing APP23/CAST mice