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CCL11 — RELA

Text-mined interactions from Literome

Clarke et al., J Immunol 2008 : In this study, we describe a novel role for protein kinase C ( PKC ) betaIotaIota in augmenting NF-kappaB mediated TNF-alpha induced transcription of the target gene CCL11 in human airway smooth muscle cells by phosphorylating the HAT p/CAF ... Studies using reporters, overexpression strategies, kinase-dead and HAT-defective mutants, and chromatin immunoprecipitation showed that PKCbetaII activation was not involved in NF-kappaB translocation, but facilitated NF-kappaB mediated CCL11 transcription by colocalizing with and phosphorylating p/CAF, and thereby acetylating histone H4 and promoting p65 association with the CCL11 promoter ... These data suggest a novel important biological role for PKCbetaIotaIota in NF-kappaB mediated CCL11 transcription by p/CAF activation and histone H4 acetylation
Jamaluddin et al., Arterioscler Thromb Vasc Biol 2009 : Eotaxin also increased the phosphorylation of Stat3 and nuclear translocation of NF-kappaB in HCAECs
Waddell et al., J Immunol 2013 (Colitis, Ulcerative...) : Intestinal CCL11 and Eosinophilic Inflammation Is Regulated by Myeloid Cell-Specific RelA/p65 in Mice