Gene interactions and pathways from curated databases and text-mining

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CCL2 — IL12A

Text-mined interactions from Literome

DePaolo et al., J Immunol 2003 : CC chemokine ligand 2 and its receptor regulate mucosal production of IL-12 and TGF-beta in high dose oral tolerance
EnrĂ­quez-de-Salamanca et al., Cytokine 2008 (Conjunctivitis, Allergic...) : TNF-alpha stimulated secretion of IL-12p40 was significantly increased by 30 min ; GM-CSF, MCP-1 , IL-6, IL-7, IL-8, and RANTES were significantly increased by 2 h, and IFN-gamma and IL-1alpha by 24 h
Goodyear et al., J Immunol 2010 (Burkholderia Infections...) : Production of IL-12 and IFN-gamma in the lungs after B. mallei infection was significantly impaired in both MCP-1 ( -/- ) and CCR2 ( -/- ) mice, whereas treatment of CCR2 ( -/- ) mice with rIFN-gamma restored protection against lethal challenge with B. mallei
Seitz et al., Eur J Immunol 1996 : In contrast, IL-12 stimulated the production of IL-1 beta and MCP-1 in TNF-alpha stimulated MNC and inhibited IL-1ra synthesis in cytokine stimulated cells
Chensue et al., J Immunol 1996 (Granuloma) : In addition, MCP-1 inhibited IL-12 production by inflammatory macrophages
Karpus et al., J Exp Med 1998 (Encephalomyelitis, Autoimmune, Experimental) : Increase in MCP-1 expression resulted in downregulation of mucosal interleukin (IL)-12 expression with concomitant increase in mucosal IL-4 expression