Gene interactions and pathways from curated databases and text-mining

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CCL7 — TNF

Text-mined interactions from Literome

Bandyopadhyay et al., Biochem Pharmacol 2006 : In MC3T3-E1 cells, apigenin dose-dependently ( from 5 to 20 microM ) inhibits TNFalpha induced production of the osteoclastogenic cytokines, IL-6 ( interleukin-6 ), RANTES ( regulated upon activation, normal T cell expressed and -secreted ), monocyte chemoattractant protein-1 ( MCP-1 ) and MCP-3
Thompson et al., Brain Res 2009 (MAP Kinase Signaling System) : This study aims to test the ability of IL-1beta and TNF-alpha to stimulate CCL2 and CCL7 protein production in rat astrocyte cultures, and to elucidate signaling pathways involved in the cytokine stimulated chemokine upregulation
Renner et al., J Neurovirol 2011 (AIDS Dementia Complex...) : Here, we demonstrate that MCP-3/CCL7 is a significant chemokine produced by astrocytes, that basal monocyte migration may be facilitated by astrocyte derived CCL7, that production of CCL7 is rapidly increased by TNF-a and thus likely plays a critical role in initiating neuroinvasion by SIV/HIV
Zhao et al., Archives of cardiovascular diseases 2013 : TFPI inhibited MCP-3 expression induced by TNF-a ; this effect may be propagated through the NF-?B pathway