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CD2 — MAPK8

Text-mined interactions from Literome

Kefaloyianni et al., J Exp Biol 2005 (Heat Stress Disorders) : In gills, both Cu2+ and Zn2+ induced a considerably higher p38-MAPK activation, which remained elevated for at least 60 min, whereas Cd2+ induced a maximal kinase activation within 60 min of treatment
Rigon et al., Neurotoxicology 2008 : Phosphorylation of p38 ( MAPK ) was enhanced by Cd(II) at all doses tested
Templeton et al., Toxicol Lett 1998 : Although Cd2+ has been reported to activate PKC in vitro, no effect was found on PKC activity in Cd2+ -treated cells, indicating the activation of MAPK by Cd2+ is through an unidentified PKC independent pathway ... We conclude that Cd2+ can cause a sustained induction of c-fos in part through sustained activation of MAPK , that contrasts with the transient activation of these species in response to physiological mitogenic stimuli