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CD28 — MAPK14

Text-mined interactions from Literome

Zhang et al., J Immunol 1999 : In contrast to that reported for human Jurkat T cells, we found that p38 MAPK , but not Jun NH2-terminal kinase (JNK), is weakly activated upon stimulation with either anti-CD3 or anti-CD28 in murine thymocytes and splenic T cells ... However, p38 MAPK is activated strongly and synergistically by either CD3/CD28 coligation or PMA/Ca2+ ionophore stimulation, which mimics TCR-CD3/CD28 mediated signaling
Marti et al., J Immunol 2001 : TCR and CD28 costimulatory receptor-cooperative induction of T cell IL-2 secretion is dependent upon activation of mitogen activated protein ( MAP ) kinases
Yu et al., J Immunol 2001 (MAP Kinase Signaling System) : Notably, CD28 ligation activated p38 MAPK and CaMKIV, the kinases stimulated by CD3 engagement, suggesting that CD28 acts by increasing the activation extent of p38 MAPK and CaMKIV