Gene interactions and pathways from curated databases and text-mining

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CD83 — IL12A

Text-mined interactions from Literome

Mosca et al., Blood 2000 : We used combinations of signaling through CD40, using CD40 ligand trimer (CD40L), and interferon gamma to demonstrate that CD83 expression is necessary but not sufficient for optimal production of IL-12 by DCs
Fedele et al., Eur J Immunol 2004 : CD38 is expressed on human mature monocyte derived dendritic cells and is functionally involved in CD83 expression and IL-12 induction
Cuéllar et al., Biomedica 2004 : The dendritic cells pre exposed to single doses of endotoxin demonstrated a reduced capacity to mature, reduced CD83 expression, inhibited secretion of IL-12 , TNFalpha, IL-10 and diminished secretion of IL-6
Xue et al., Int Immunopharmacol 2013 : We elucidated that IFN-? up-regulated the expression of MHC II, CD40, CD80, CD83 and CD86 molecules on BMDCs, down-regulated the activity of pinocytosis and phagocytosis by BMDCs, and induced higher levels of IL-12 and TNF-a secreted by BMDCs