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CDH17 — SRC
Text-mined interactions from Literome
Weis et al., J Clin Invest 2004
(Edema...) :
Src blockade
stabilizes a
Flk/cadherin complex, reducing edema and tissue injury following myocardial infarction
Wallez et al., Oncogene 2007
:
Finally, we found that in a VEGF induced wound healing assay,
cadherin adhesive activity was
impaired by
Src kinase inhibitors
McLachlan et al., Mol Biol Cell 2007
:
Finally, our data implicate PI3-kinase signaling as a target for
cadherin activated
c-Src signaling that contributes to its positive impact on cadherin function
McLachlan et al., Cytoskeleton (Hoboken, N.J.) 2011
:
Additionally, vanadate treatment phenocopied the effects of Src inhibition on the actin cytoskeleton, suggesting that PTP activity is required for the dynamic regulation of the actin cytoskeleton by
cadherin activated
Src signaling
Yan et al., Stroke 2013
(Subarachnoid Hemorrhage) :
Downstream to PAR-1,
c-Src dependent activation of p21 activated kinase-1
led to an increased serine/threonine phosphorylation of vascular
endothelial-cadherin ; immunoprecipitation results revealed an enhanced binding of phosphorylated vascular endothelial-cadherin with endocytosis orchestrator ß-arrestin-2