Gene interactions and pathways from curated databases and text-mining

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CEP135 — EPHB2

Text-mined interactions from Literome

Kujime et al., J Immunol 2000 : SB 203580, PD 98059, and CEP-1347 attenuated IV-infection induced p38 MAP kinase activity, Erk activity, and JNK activity, respectively
Hashimoto et al., Am J Respir Crit Care Med 2001 : The results showed that : ( 1 ) TGF-beta1 caused the phenotypic modulation of HLF to myofibroblasts in a dose- and a time dependent manner ; ( 2 ) TGF-beta1 induced increases in c-Jun-NH2- terminal kinase (JNK), p38 MAPK, and extracellular signal regulated kinase ( Erk ) phosphorylation and activity ; ( 3 ) the inhibitors CEP-1347, SB 203580, and PD 98059 attenuated TGF-beta1 induced JNK, p38 MAPK, and Erk activity, respectively ; and ( 4 ) CEP-1347 , but not SB 203580 or PD 98059, attenuated the TGF-beta1 induced phenotypic modulation of HLF to myofibroblasts in a dose dependent manner
Bisel et al., J Cell Biol 2008 : ERK regulates Golgi and centrosome orientation towards the leading edge through GRASP65
Colello et al., J Biol Chem 2012 (MAP Kinase Signaling System) : Integrins regulate microtubule nucleating activity of centrosome through mitogen activated protein kinase/extracellular signal regulated kinase kinase/extracellular signal regulated kinase ( MEK/ERK ) signaling