Gene interactions and pathways from curated databases and text-mining

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CEP192 — JAK2

Text-mined interactions from Literome

Plo et al., Blood 2008 (Myeloproliferative Disorders...) : Moreover, JAK2 activation increased centrosome and ploidy abnormalities
Santos et al., Blood 2010 (Polycythemia Vera...) : Phase 2 study of CEP-701 , an orally available JAK2 inhibitor , in patients with primary or post-polycythemia vera/essential thrombocythemia myelofibrosis
Stump et al., Arthritis Res Ther 2011 (Arthritis, Experimental...) : In this paper, we describe the efficacy profile of CEP-33779 , a highly selective, orally active, small-molecule inhibitor of JAK2 evaluated in two mouse models of RA