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AKT1 — CNR1
Text-mined interactions from Literome
Samson et al., J Immunol 2003
:
CB1 inhibition does not
affect AKT or extracellular signal regulated kinase activation by cannabinoids, indicating that CB2 is the predominant regulatory receptor for these kinases in this cell context
Catani et al., Cell Mol Life Sci 2010
:
Anandamide extends platelets survival through
CB(1) dependent
Akt signaling ... Instead, AEA binding to type-1
cannabinoid receptor activates
Akt , which regulates, through phosphorylation of Bad, the interactions among different Bcl-2 family members
Preet et al., Cancer prevention research (Philadelphia, Pa.) 2011
(Carcinoma, Non-Small-Cell Lung...) :
Upon further elucidation into the molecular mechanism, we observed that both
CB1 and CB2 agonists
inhibited phosphorylation of
AKT , a key signaling molecule controlling cell survival, migration, and apoptosis, and reduced matrix metalloproteinase 9 expression and activity
Wu et al., Bone 2011
:
CB1 signaling
regulated JNK, ERK, GSK-3ß, and
Akt activation as well as Runx2 and IGF-I expression