Gene interactions and pathways from curated databases and text-mining

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COQ4 — TNF

Text-mined interactions from Literome

Schmelzer et al., Biofactors 2008 (Inflammation) : To test this hypothesis, we studied the effect of CoQ10 on the NFkappaB1 dependent pro-inflammatory cytokine TNF-alpha ... In the presence of 2.5 microM or 75 microM CoQ10 the LPS induced TNF-alpha response was significantly reduced to 73.3 +/- 2.8 % and 74.7 +/- 8.9 % in apoE3 or apoE4 cells, respectively
Gökbel et al., J Med Food 2010 : Both CoQ10 and placebo supplementation did not affect plasma adiponectin and TNF-alpha levels
Díaz-Castro et al., Eur J Nutr 2012 (Inflammation) : Data obtained also indicate that CoQ ( 10 ) prevents over-expression of TNF-a after exercise, together with an increase in sTNF-RII that limits the pro-inflammatory actions of TNF