◀ Back to PRKAR1B

CPT2 — PRKAR1B

Text-mined interactions from Literome

Tiwari et al., Blood 2004 (Leukemia, Lymphocytic, Chronic, B-Cell) : The EPAC-specific cAMP analog 8CPT-2Me-cAMP ( 8- ( 4-chloro-phenylthio ) -2'-O-methyladenosine-3',5'-cAMP ) activates Rap1 in B-CLL cells, but, unlike rolipram/forskolin or 8-Bromo-cAMP, it does not induce PKA activation, as judged by phosphorylation of the transcription factor cAMP-response element binding protein ( CREB )
Shimomura et al., Arch Biochem Biophys 2004 : PKA activation by 8CPT-2Me-cAMP was 100-fold lower than that by cAMP
Lo et al., J Orthop Res 2011 : By using different target-specific cAMP analogs : 8-CPT-2Me-cAMP which specifically activates exchange protein activated by cAMP ( Epac ), and 6-Bnz-cAMP which specifically activates protein kinase A (PKA) , we observed that the PKA signaling pathway plays a dominant role in this process