◀ Back to CASP1
CASP1 — CRYAB
Text-mined interactions from Literome
Ikeda et al., Biol Pharm Bull 2006
:
The small heat shock protein
alphaB-crystallin inhibits differentiation induced
caspase 3 activation and myogenic differentiation ... Overexpression of
alphaB-crystallin in C2C12 cells
suppressed differentiation induced apoptosis and activation of
caspase 3, and also decreased the expression of MyoD and myogenin during myogenic differentiation of C2C12 cells induced by the differentiation medium ... Our findings suggest that stress such as growth factor deprivation plays an important role in triggering apoptosis associated with myogenic differentiation and
alphaB-crystallin suppressed the differentiation, apoptosis and
caspase 3 activity
Sanbe et al., PloS one 2011
(Ion Channel Gating) :
Nicorandil treatment also inhibited the increase in BAX, the decrease in BCL2,
activation of
caspase-3 and apoptotic cell death by mutant
HSPB5