Gene interactions and pathways from curated databases and text-mining

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CSK — MAPK15

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Zagozdzon et al., Cell Signal 2006 (MAP Kinase Signaling System) : In this work, we compared the effect of CHK versus Csk on MAPK signaling and elucidated the signaling pathway mediated by CHK leading to the activation of Erk1/2
Choudhury et al., Cell Signal 2006 : Inhibition of c-Src tyrosine kinase blocked PDGF stimulated MAPK activity and resulted in attenuation of c-fos gene transcription with concomitant prevention of Elk-1 transactivation
Beaulieu et al., Blood 2011 : Using Meg-01 cells and mouse megakaryocytes, we found that NF?B, ERK-MAPK , and PI3K/Akt pathways, known downstream pathways of TLRs, are activated by Pam3CSK4 , a TLR2-specific ligand