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CSN2 — NFKB1

Text-mined interactions from Literome

Kweon et al., Biochem Biophys Res Commun 2006 (Inflammation...) : Moreover, casein kinase 2 ( CK2 ) is involved in synergistic induction of NF-kappaB via a mechanism dependent on phosphorylation of p65 at both Ser536 and Ser276 sites
Schweitzer et al., EMBO J 2007 : CSN controls NF-kappaB by deubiquitinylation of IkappaBalpha ... For the first time, we show here an inducible interaction of the CSN with IkappaBalpha and that the CSN controls IkappaBalpha and NF-kappaB activity ... Strikingly, disruption of the CSN by a small interfering RNA mediated knockdown of single CSN subunits results in a reduced re-accumulation of IkappaBalpha and prolonged nuclear translocation of NF-kappaB in TNFalpha stimulated cells
Wu et al., Cancer Cell 2009 (Cell Transformation, Neoplastic...) : We demonstrated that NF-kappaB is required for the induction of COP9 signalosome 2 (CSN2) , which, in turn, blocks the ubiquitination and degradation of Snail
Willems et al., Molecular cancer 2010 (Liposarcoma, Myxoid) : Kinome profiling of myxoid liposarcoma reveals NF-kappaB-pathway kinase activity and casein kinase II inhibition as a potential treatment option