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CXCL9 — RELA
Text-mined interactions from Literome
Méndez-Samperio et al., J Interferon Cytokine Res 2002
:
Finally, two specific
NF-kappa B inhibitors, sulfasalazine and caffeic acid phenetyl ester ( CAPE ), strongly
inhibited the production of
CXCL-8 by human monocytes infected with M. bovis
Hiroi et al., Biochem J 2003
(Carcinoma...) :
Activation of
NF-kappaB in Ca9-22 cells
restored the expression of IFNgamma stimulated
CXCL9 and CXCL10 mRNAs ... These results indicate that constitutive
NF-kappaB activity, which is often associated with tumour development, is
required for the induced expression of
CXCL9 and CXCL10 genes in human tumour cell lines in response to IFNgamma
Chandrasekar et al., J Biol Chem 2004
(Arteriosclerosis...) :
In conclusion,
CXCL16 is a potent and direct
activator of
NF-kappaB and induces kappa B-dependent proinflammatory gene transcription
Si et al., J Immunol 2004
(Acquired Immunodeficiency Syndrome) :
Interestingly, although LPS induced
IL-8/CXCL8 was
dependent on
NF-kappaB , the baseline or 15d-PGJ ( 2 ) -mediated IL-8/CXCL8 production was NF-kappaB independent
Cinatl et al., Int J Mol Med 2005
(Colonic Neoplasms...) :
High hydrocortisone concentrations ( > or =50 microg/ml ) completely prevented increased DNA binding activity of AP-1 and
NF-kappaB and
inhibited up-regulation of
CXCL8 and CXCL10, but did not reduce chemokine expression to basal levels
Keshamouni et al., Neoplasia (New York, N.Y.) 2005
(Carcinoma, Non-Small-Cell Lung...) :
Similarly, an inhibitor of
NF-kappa B activation ( PDTC ) also
blocked CXCL8 , CXCL5, and CXCL1 production, consistent with their NF-kappa B-dependent regulation
Edwards et al., Mol Immunol 2007
:
Focusing on CXCL8, both rhinovirus infection and dsRNA treatment
required IkappaB kinase-beta for induction of
CXCL8
D'Aversa et al., J Neurosci Res 2008
(AIDS Dementia Complex...) :
Gel shift analyses demonstrated that
NFkappaB and AP-1, but not C/EBPbeta,
mediate microglial
CXCL8 production
Yang et al., Mol Immunol 2008
(Escherichia coli Infections...) :
Bovine TLR2 and TLR4 properly transduce signals from Staphylococcus aureus and E. coli, but S. aureus fails to both activate
NF-kappaB in mammary epithelial cells and to quickly
induce TNFalpha and interleukin-8 (
CXCL8 ) expression in the udder
Bischoff et al., J Cell Biochem 2008
:
NF-kappaB inhibition
resulted in a decrease in
CXCL8 levels in hMSCs grown in non-OGM
Martin et al., J Biol Chem 2009
:
Furthermore, we identified the components of the CBM complex, Carma3, Bcl10, and Malt1, as key mediators of the
CXCL8/IL8 induced
NFkappaB activation and VEGF up-regulation
Ho et al., J Immunol 2009
:
In contrast, NE did not induce NRF expression in A549 and Beas-2B cells, where NE only stimulates
NF-kappaB activation and
IL-8/CXCL8 induction
Khalaf et al., BMC immunology 2010
(Inflammation) :
The present study shows that
NF-kappaB regulated IL-6 but not
CXCL8