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CYP2J2 — JUN

Text-mined interactions from Literome

Marden et al., Biochem J 2003 (Anoxia) : Mutagenesis of the -56/-63 element abolished most, but not all, of the activation of CYP2J2 by c-Jun , thus implicating an additional site within the c-Jun-responsive region ... The present results establish an important role for c-Jun in the control of CYP2J2 expression in liver cells
Marden et al., Biochem J 2005 : Recent studies have indicated that AP-1 ( activator protein-1 ) regulates CYP2J2 expression in normoxia and hypoxia ... Down-regulation of CYP2J2 in hypoxic HepG2 cells was closely associated with the up-regulation of c-fos and transient transfection analysis demonstrated that c-Fos abolishes the activation of CYP2J2 by the AP-1 protein c-Jun
Lee et al., Mol Pharmacol 2010 : Up-regulation of human CYP2J2 in HepG2 cells by butylated hydroxyanisole is mediated by c-Jun and Nrf2 ... In the present study, we tested the hypothesis that CYP2J2 expression may be activated in cells by c-Jun/Nrf2 heterodimers