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Text-mined interactions from Literome

Tomita et al., Respirology 2002 : Lipopolysaccharide induced gene expression of hBD-2 was down-regulated by ( i ) dexamethasone, ( ii ) inhibition of NF-kappaB and AP-1 , and ( iii ) intracellular calcium chelator ... These findings suggest that glucocorticoids ( GC ), but not COX inhibitors, reduce hBD-2 gene expression, while NF-kappaB, AP-1 and intracellular calcium are essential for hBD-2 expression
Wehkamp et al., Infect Immun 2004 : NF-kappaB- and AP-1 mediated induction of human beta defensin-2 in intestinal epithelial cells by Escherichia coli Nissle 1917 : a novel effect of a probiotic bacterium ... Luciferase gene reporter analyses and site directed mutagenesis experiments demonstrated that functional binding sites for NF-kappaB and AP-1 in the hBD-2 promoter are required for induction of hBD-2 through E. coli Nissle 1917
Voss et al., J Biol Chem 2006 (Crohn Disease) : Luciferase gene reporter analyses and site directed mutagenesis experiments demonstrated that functional binding sites for NF-kappaB and AP-1 in the hBD-2 promoter are required for NOD2 mediated induction of hBD-2 through MDP
Wehkamp et al., J Invest Dermatol 2006 : Pseudomonas aeruginosa- and IL-1beta mediated induction of human beta-defensin-2 in keratinocytes is controlled by NF-kappaB and AP-1
Kanda et al., Am J Physiol Cell Physiol 2007 : These results suggest that histamine stimulates H1 receptor and potentiates TNF-alpha- or IFN-gamma induced hBD-2 production dependent on NF-kappaB, AP-1 , or STAT1 in human keratinocytes
Yoon et al., Infect Immun 2010 : In contrast, suppression of AP-1 did not affect hBD-2 expression in BFT stimulated cells