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DRG2 — EPHB2
Text-mined interactions from Literome
Obata et al., Neuroscience 2004
(Pain...) :
Therefore, we suggest that after inflammation near the cell body, NGF synthesized within the nerve root and
DRG induces BDNF expression through trkA receptors and intracellular
ERK-MAPK
Doya et al., Spine (Phila Pa 1976) 2005
(Wounds, Nonpenetrating) :
ERK is
activated by phosphorylation in the
DRG and spinal cord by noxious stimuli, which are related to pain hypersensitivity
Kato et al., Neurosci Res 2007
:
Co-culture studies suggested that
dorsal root ganglion ( DRG ) activated
ERK in the dorsal horn ... Brain derived neurotrophic factor (BDNF) activated ERK in the dorsal horn, and anti-BDNF blocked the
DRG induced
ERK activation ... These results suggest roles of BDNF in the
DRG induced
ERK activation in the embryonic dorsal horn
Ke et al., Am J Physiol Endocrinol Metab 2013
(Bone Resorption) :
Inhibition of these proteins abolished the effects of DRG2 on formation of large OCs with actin rings, implying that
DRG2 affects cytoskeleton reorganization in a
Rac1/Rho/ERK/Akt dependent manner