◀ Back to RELA
ETS1 — RELA
Text-mined interactions from Literome
Lee et al., Infect Immun 2005
:
Our data indicate that the increased Ets/Elk and
NF-kappaB promoter activities associated with M. smegmatis infected macrophages are responsible, at least in part, for the increased TNF-alpha and NOS2 production observed in these infected cells and that ERK1/2 is
required for
Ets/Elk activity and full TNF-alpha production
Sangiovanni et al., PloS one 2013
:
In vitro,
ETs inhibited TNF-a induced NF-kB driven transcription ( IC50 : 0.67-1.73 µg/mL ) and
reduced TNF-a induced
NF-kB nuclear translocation ( 57 % -67 % at 2 µg/mL )
Newton et al., FEBS Lett 1997
:
Furthermore, equivalent effects were observed on
NF-kappaB binding to COX-2 promoter kappaB sites and
activation of the Jun N-terminal kinases (JNK),
p54 and p46