Gene interactions and pathways from curated databases and text-mining

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F2RL2 — IL8

Text-mined interactions from Literome

Wang et al., Int J Biochem Cell Biol 2006 : It was found that HDFs express PAR-1 and PAR-3 , and thrombin induces approximately 7.4-fold increase in IL-8 secretion from HDFs. Hirudin and a PAR-1 blocking antibody completely abolish the action of thrombin
Lee et al., Ann Allergy Asthma Immunol 2010 (Asthma) : Both PAR-2 and PAR-3 might play a role in CraA induced IL-8 secretion from human airway epithelial cells