UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

NCI Pathway Database CDC42 signaling events: CDC42/GTP complex (CDC42) → PKC epsilon/Par3/Par6/CDC42/GTP complex (PRKCE-F2RL2-PARD6A-CDC42) (modification, collaborate)
Koh et al., J Cell Sci 2008, Koh et al., J Cell Sci 2009
Evidence: mutant phenotype, physical interaction
NCI Pathway Database CDC42 signaling events: CDC42/GTP complex (CDC42) → PKC epsilon/Par3/Par6 complex (PRKCE-F2RL2-PARD6A) (modification, collaborate)
Koh et al., J Cell Sci 2008, Koh et al., J Cell Sci 2009
Evidence: mutant phenotype, physical interaction
NCI Pathway Database CDC42 signaling events: PKC epsilon/Par3/Par6/CDC42/GTP complex (PRKCE-F2RL2-PARD6A-CDC42) → PKC epsilon/Par3/Par6 complex (PRKCE-F2RL2-PARD6A) (modification, collaborate)
Koh et al., J Cell Sci 2008, Koh et al., J Cell Sci 2009
Evidence: mutant phenotype, physical interaction
NCI Pathway Database CDC42 signaling events: PKC epsilon/Par3/Par6/CDC42/GTP complex (PRKCE-F2RL2-PARD6A-CDC42) → PAK2-PAK4 (PAK4/PAK2) (modification, activates) Koh et al., J Cell Sci 2008, Koh et al., J Cell Sci 2009
Evidence: assay
NCI Pathway Database CDC42 signaling events: PKC epsilon/Par3/Par6/CDC42/GTP complex (PRKCE-F2RL2-PARD6A-CDC42) → Src-Yes (YES1/SRC) (modification, activates) Koh et al., J Cell Sci 2008, Koh et al., J Cell Sci 2009
Evidence: assay