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FOXP3 — JUN
Pathways - manually collected, often from reviews:
-
NCI Pathway Database Calcineurin-regulated NFAT-dependent transcription in lymphocytes:
NFAT1/FOXP3 complex (NFATC2-FOXP3)
→
JUN/FOS/NFAT1 complex (FOS-JUN-NFATC2)
(transcription, inhibits)
Wu et al., Cell 2006
Evidence: mutant phenotype, reporter gene, physical interaction, other species
-
NCI Pathway Database Calcineurin-regulated NFAT-dependent transcription in lymphocytes:
NFAT1/FOXP3 complex (NFATC2-FOXP3)
→
JUN/FOS/NFAT1 complex (FOS-JUN-NFATC2)
(modification, collaborate)
Wu et al., Cell 2006
Evidence: mutant phenotype, physical interaction, other species
-
NCI Pathway Database Calcineurin-regulated NFAT-dependent transcription in lymphocytes:
NFAT1/FOXP3 complex (NFATC2-FOXP3)
→
JUN (JUN)
(modification, collaborate)
Wu et al., Cell 2006
Evidence: mutant phenotype, physical interaction, other species
-
NCI Pathway Database Calcineurin-regulated NFAT-dependent transcription in lymphocytes:
FOXP3 (FOXP3)
→
JUN/FOS/NFAT1 complex (FOS-JUN-NFATC2)
(modification, collaborate)
Wu et al., Cell 2006
Evidence: mutant phenotype, physical interaction, other species
-
NCI Pathway Database Calcineurin-regulated NFAT-dependent transcription in lymphocytes:
FOXP3 (FOXP3)
→
JUN (JUN)
(modification, collaborate)
Wu et al., Cell 2006
Evidence: mutant phenotype, physical interaction, other species
Text-mined interactions from Literome
Liu et al., Cancer Res 2009
(Mammary Neoplasms, Experimental) :
Activating transcription factor 2 and
c-Jun mediated induction of
FoxP3 for experimental therapy of mammary tumor in the mouse
Chen et al., J Dermatol Sci 2013
(MAP Kinase Signaling System...) :
Next we found that
phospho-c-JUN ( ser63/73 ), main downstream of JNK pathway, could interact with FOXP3 and
promoted FOXP3 nuclear translocation