Gene interactions and pathways from curated databases and text-mining

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FUT2 — IL8

Text-mined interactions from Literome

Sugita et al., Res Commun Mol Pathol Pharmacol 1999 : We investigated the effect of FUT-175 , a serine protease inhibitor, on the production of pro-inflammatory cytokines, interleukin-6 (IL-6) and interleukin-8 (IL-8), by monocytes stimulated with lipopolysaccharide (LPS) ... We investigated the effect of FUT-175 , a serine protease inhibitor, on the production of pro-inflammatory cytokines, interleukin-6 (IL-6) and interleukin-8 (IL-8) , by monocytes stimulated with lipopolysaccharide (LPS) ... The productions of both IL-6 and IL-8 , measured by enzyme linked immunosorbent assay, were significantly inhibited by FUT at the concentration of 1 to 100 microg/ml in a dose dependent manner ... Furthermore, the expressions of IL-6 and IL-8 mRNAs were also inhibited by FUT-175
Kikuchi et al., Res Commun Mol Pathol Pharmacol 1995 : IL-8 production by PMN and vascular endothelial cells stimulated with lipopolysaccharide (LPS) was inhibited by FUT-175