Gene interactions and pathways from curated databases and text-mining

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AKT1 — GAPDH

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Shen et al., J Am Soc Nephrol 2006 : Expression of a constitutively active Akt increased GAPDH and pax2 abundance
Yao et al., J Cell Physiol 2012 (Starvation) : Inhibition of Akt prevented PE-induced GAPDH activity increase and cardiomyocytes protection
Leisner et al., Oncogene 2013 (MAP Kinase Signaling System...) : In defining each pathway 's contributions, we found that AKT inhibition alone maximally induced GAPDH nuclear accumulation, whereas MEK/ERK inhibition alone had no effect on GAPDH localization